Beta-catenin(PT2250) mouse mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: N1868

Reactivity:Human,Mouse

Applications:IHC-p,IF(paraffin section)

Modification:Unmodfied/ Total

Source:Monoclonal Mouse/IgG2b,Kappa

Storage and Stability:-20°C/1 year

Size:

Price/Quantity $190

Quantity:

Datasheet

SDS

Immunohistochemical

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Beta-catenin(PT2250) mouse mAb

Ma. Zhan. Shuping Lou. and Zheng Jiang. "PHLDA2 regulates EMT and autophagy in colorectal cancer via the PI3K/AKT signaling pathway." Aging (Albany NY) 12.9 (2020): 7985.

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Lead Time

Antibodies 1-2 business day, ELISA kits 2-3 business day lead time

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Product Details

Product Name

Beta-catenin(PT2250) mouse mAb

Description

catenin beta 1(CTNNB1) Homo sapiens. The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016],

Catalog No

N1868

Reactivity

Human, Mouse

Applications

IHC-p,IF(paraffin section)

Modification

Unmodfied/ Total

Source

Monoclonal Mouse/IgG2b, Kappa

Dilution

IHC-p 1:100-500，WB 1:500-2000

Purification

The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Concentration

Storage and Stability

-20°C/1 year

Other Name

Molecular Weight (Da)

Gene Name

CTNNB1 CTNNB OK/SW-cl.35 PRO2286

Protein Name

Catenin beta-1 (Beta-catenin)

Human Gene ID

1499

Human Swiss Prot No.

P35222

Immunogen

Synthesized peptide derived from human Beta-catenin

Specificity

This antibody detects endogenous levels of human Catenin beta-1 (Beta-catenin). Heat-induced epitope retrieval (HIER) TRIS-EDTA of pH9.0 was highly recommended as antigen repair method in paraffin section

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.