Thyroid transcription factor-1 (TTF1) mouse mAb(PT2256)

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Catalog No: N1878

Reactivity:Human,Mouse

Applications:IHC-p,IF(paraffin section)

Modification:Unmodfied/ Total

Source:Monoclonal Mouse/IgG2b,Kappa

Storage and Stability:-20°C/1 year

Size:

Price/Quantity $190

Quantity:

Datasheet

SDS

Immunohistochemical

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Thyroid transcription factor-1 (TTF1) mouse mAb(PT2256)

Immunohistochemical analysis of paraffin-embedded human Lung adenocarcinoma Antibody was diluted at 1:200(4° overnight).

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Lead Time

Antibodies 1-2 business day, ELISA kits 2-3 business day lead time

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Product Details

Product Name

Thyroid transcription factor-1 (TTF1) mouse mAb(PT2256)

Description

NK2 homeobox 1(NKX2-1) Homo sapiens. This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares the symbol/alias 'TTF1' with another gene, transcription termination factor 1, which plays a role in ribosomal gene transcription. [provided by RefSeq, Feb 2014],

Catalog No

N1878

Reactivity

Human, Mouse

Applications

IHC-p,IF(paraffin section)

Modification

Unmodfied/ Total

Source

Monoclonal Mouse/IgG2b, Kappa

Dilution

WB 500-2000 IHC-p 1:100-500

Purification

The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Concentration

Storage and Stability

-20°C/1 year

Other Name

Homeobox protein Nkx-2.1 (Homeobox protein NK-2 homolog A) (Thyroid nuclear factor 1) (Thyroid transcription factor 1) (TTF-1)

Molecular Weight (Da)

Gene Name

NKX2-1 NKX2A TITF1 TTF1

Protein Name

Thyroid transcription factor-1 (TTF1)

Human Gene ID

7080

Human Swiss Prot No.

P43699

Immunogen

Synthesized peptide derived from human Thyroid transcription factor-1 (TTF1)

Specificity

This antibody detects endogenous levels of human Thyroid transcription factor-1 (TTF1). Heat-induced epitope retrieval (HIER) TRIS-EDTA of pH9.0 was highly recommended as antigen repair method in paraffin section

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.