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> Products > Primary Antibodies > Anti-Human Cytokeratin 8 (ABT536) Mouse Monoclonal Antibody

Anti-Human Cytokeratin 8 (ABT536) Mouse Monoclonal Antibody

Overview Description
Datasheet SDS
   Immunohistochemical   
Catalog No : V0492
  • Reactivity
    Human,M
  • Application
    IHC,WB
  • Modification
    Unmodified/ Total
  • Source
    Monoclonal Mouse
  • Storage and Stability
    Stable at -20°C for at least 1 year.
  • Size
    0.05ml
  • Price/Quantity
    $95
  • Quantity
Add to Cart
Details
  • Product Name
    Anti-Human Cytokeratin 8 (ABT536) Mouse Monoclonal Antibody
  • Description
    Cytokeratin 8 (CK8) is a member of the type II family of cytokeratins with a molecular weight of 53 kDa which plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. It generally exists in monolayer and pseudostratified epithelium, and is expressed in glandular epithelium, transitional epithelium and hepatocytes. It is absent in squamous cell carcinomas. CK8 dimerizes with CK18 to form an intermediate filament in simple single-layered epithelial cells. CK8/18 expression patterns are useful for classification of tumors of unknown origin and poorly differentiated carcinomas.
  • Catalog No
    V0492
  • Reactivity
    Human, M
  • Application
    IHC,WB
  • Modification
    Unmodified/ Total
  • Source
    Monoclonal Mouse
  • Storage and Stability
    Stable at -20°C for at least 1 year.
  • Other Name
    CARD2, CK 8, CK-8, CK8, CYK8, CYKER, Cytokeratin endo A, Cytokeratin-8, DreK8, EndoA, K2C8, K2C8_HUMAN, K8, Keratin 8, Keratin type II cytoskeletal 8, Keratin, type II cytoskeletal 8, Keratin-8, KO, Krt 2.8, KRT8, MGC118110, MGC174782, MGC53564, MGC85764, sb:cb186, Type-II keratin Kb8
  • Gene Name
    KRT8
  • UniProtKB
    P05787
  • Clone ID
    ABT536
  • Isotype
    IgG2a, kappa
  • Localization
    Cytoplasmic, Membranous
  • Positive Tissue Control
    Liver/ Tonsil
  • Specificity
    The antibody can specifically recognize human CK8 protein, and shows no cross reaction with CK1, 4, 5, 6, 7, 10, 15, 16, 17, 18, 20.
  • Formulation
    PBS, pH7.2, 0.03% Proclin 300, 50% glycerol
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Application Data
HepG2 whole cell lysates were separated by 10% SDS-PAGE, and the membrane was blotted with anti-CK8 (ABT536)antibody. The HRP-conjugated Goat anti-Mouse IgG(H + L) antibody was used to detect the antibody. Lane 1: HepG2 Predicted band size: 54kDa Observed band size: 54kDa
Application Data
SW480 whole cell lysates were separated by 10% SDS-PAGE, and the membrane was blotted with anti-CK8(ABT536)antibody. The HRP-conjugated Goat anti-Mouse IgG(H + L) antibody was used to detect the antibody. Lane 1: SW480 Predicted band size: 54kDa Observed band size: 50kDa
Application Data
Human lung adenocarcinoma tissue was stained with Anti-Cytokeratin 8 (ABT536) Antibody
Application Data
Human colon carcinomatissue was stained with Anti-Cytokeratin 8 (ABT536) Antibody
Application Data
Human gastric adenocarcinoma tissue was stained with Anti-Cytokeratin 8 (ABT536) Antibody
Application Data
Human appendix tissue was stained with Anti-Cytokeratin 8 (ABT536) Antibody
Application Data
Human liver tissue was stained with Anti-Cytokeratin 8 (ABT536) Antibody

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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