Vimentin is the most common member of intermediate filament protein family. It is a main component of cytoskeleton structure. Its main function is to maintain cell integrity and skeleton stability. It is expressed in mesenchymal cells and mesoderm derived cells. Vimentin is a relatively specific marker of mesenchymal cells and their derived tumors.
Catalog No
V0476
Reactivity
Human, M
Application
IHC,WB
Modification
Unmodified/ Total
Source
Monoclonal Mouse
Storage and Stability
Stable at -20°C for at least 1 year.
Other Name
CTRCT30, Epididymis luminal protein 113, FLJ36605, HEL113, VIM, VIME_HUMAN, Vimentin
Gene Name
VIM
UniProtKB
P08670
Clone ID
ABT281
Isotype
IgG1, Kappa
Localization
Cytoplasmic
Positive Tissue Control
Tonsil/ Liver
Specificity
The antibody can specifically recognize human Vimentin protein. In western blotting of Hela cell lysate, the antibody can label a 54 kDa band corresponding to Vimentin.