Oct-2 is a B-cell transcription factor that binds to coactivator Bob. 1 to activate the transcription of immunoglobulin gene. It plays a role in the formation of germinal centers and the differentiation of B cells into plasma cells. OCT2 is highly expressed in all mature B cells and low expressed in pre-B cells, T cells and myeloid cells. It is a marker of B cell differentiation. It can be used to identify B cells and B-cell lymphoma.
Catalog No
V0423
Reactivity
Human
Application
IHC
Modification
Unmodified/ Total
Source
Monoclonal Mouse
Storage and Stability
Stable at -20°C for at least 1 year.
Other Name
class 2, Lymphoid restricted immunoglobulin octamer binding protein, Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2, NF A2, Oct 2, Oct-2, Octamer binding transcription factor 2, Octamer-binding protein 2, Octamer-binding transcription factor 2, OTF-2, OTF2, PO2F2_HUMAN, POU domain, POU domain class 2 transcription factor 2, POU2F2, transcription factor 2
Gene Name
POU2F2
UniProtKB
P09086
Clone ID
ABT211
Isotype
IgG2b, kappa
Localization
Nuclear
Positive Tissue Control
Tonsil/ Appendix
Specificity
The antibody can specifically recognize human Oct-2 protein.
