Androgen receptor (AR) is a member of the ligand response transcription regulator superfamily, which is expressed in prostate, testis and sweat gland. Upon AR binding the receptor, it stimulates androgen responsive genes transcription. AR plays an important role in the occurrence and development of prostate cancer. The higher the degree of differentiation of prostate cancer tissue, the higher the expression of AR, and the hormone treatment effect of positive prostate cancer patients is better. AR is mainly used for the detection of prostate cancer, guiding clinical treatment, and can also be used for other cancers such as esophageal cancer and breast cancer.
Catalog No
V0179
Reactivity
Human
Application
IHC,WB
Modification
Unmodified/ Total
Source
Monoclonal Mouse
Storage and Stability
Stable at -20°C for at least 1 year.
Other Name
AIS, Androgen receptor, AR, AR8, DHTR, Dihydro testosterone receptor, Dihydrotestosterone receptor (DHTR), HUMARA, HYSP1, KD, NR3C4, Nuclear receptor subfamily 3 group C member 4 (NR3C4), Nuclear receptor subfamily 3 group C member 4, SBMA, SMAX1, Spinal and bulbar muscular atrophy (SBMA), Spinal and bulbar muscular atrophy, Testicular Feminization (TFM), TFM
Gene Name
AR
UniProtKB
P10275
Clone ID
ABT101
Isotype
IgG2b, kappa
Localization
Nuclear
Positive Tissue Control
Prostate
Specificity
The antibody can specifically recognize human AR protein.
Lncap whole cell lysates were separated by 10% SDS-PAGE, and the membrane was blotted with anti-AR(ABT101)antibody. The HRP-conjugated Goat anti-Mouse IgG(H + L) antibody was used to detect the antibody.
Lane 1: Lncap
Predicted band size: 98kDa
Observed band size: 98kDa
