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Acetyl-Lys proteins Antibody
Acetyl-Lys proteins Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: D0020
Reactivity:Human,Mouse,Rat,Monkey,plant
Applications:WB,IHC,IF,ELISA
Modification:Acetyl Specific
Source:Store at -20°C/1 year
Storage and Stability:

$205
Product Details
Product Name
Acetyl-Lys proteins Antibody
Description
Acetylation of lysine, like phosphorylation of serine, threonine or tyrosine, is an important reversible modification controlling protein activity. The conserved amino-terminal domains of the four core histones (H2A, H2B, H3, and H4) contain lysines that are acetylated by histone acetyltransferases (HATs) and deacetylated by histone deacetylases (HDACs). Signaling resulting in acetylation/deacetylation of histones, transcription factors, and other proteins affects a diverse array of cellular processes including chromatin structure and gene activity, cell growth, differentiation, and apoptosis. Recent proteomic surveys suggest that acetylation of lysine residues may be a widespread and important form of posttranslational protein modification that affects thousands of proteins involved in control of cell cycle and metabolism, longevity, actin polymerization, and nuclear transport. The regulation of protein acetylation status is impaired in cancer and polyglutamine diseases, and HDACs have become promising targets for anti-cancer drugs currently in development.
Catalog No
D0020
Reactivity
Human, Mouse, Rat, Monkey, plant
Source
Polyclonal, Rabbit,IgG
Modification
Acetyl Specific
Applications
WB, IHC, IF, ELISA
Dilution
WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
Store at -20°C/1 year
Other Name
Molecular Weight (Da or kDa)
Gene Name
Protein Name
Human Gene ID
Human Swiss Prot No.
Immunogen
Synthesized acetyl-peptide derived from human acetylation Lys proteins.
Specificity
Acetyl-Lys proteins Polyclonal Antibody detects endogenous levels of acetylated Lys proteins.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Publications (1)