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Primary Antibodies
PKAα/β/γ cat Antibody
PKAα/β/γ cat Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: B0548
Reactivity:Human,Mouse,Rat,Pig
Applications:WB,IHC,IF,ELISA
Modification:Unmodified/Total
Source:Polyclonal,Rabbit,IgG
Storage and Stability:Store at -20°C/1 year

$205
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Kinases and Phosphatases
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PKAα/β/γ cat Antibody

Immunofluorescence analysis of Hela cell. 1,PKAα/β/γ cat Polyclonal Antibody(green) was diluted at 1:200(4° overnight). 2, Goat Anti Rabbit Alexa Fluor 488 Catalog:SA0665 was diluted at 1:1000(room temperature, 50min). 3 DAPI(blue) 10min.

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Product Details
Product Name
PKAα/β/γ cat Antibody
Description
This gene encodes one of the catalytic subunits of protein kinase A, which exists as a tetrameric holoenzyme with two regulatory subunits and two catalytic subunits, in its inactive form. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. cAMP-dependent phosphorylation of proteins by protein kinase A is important to many cellular processes, including differentiation, proliferation, and apoptosis. Constitutive activation of this gene caused either by somatic mutations, or genomic duplications of regions that include this gene, have been associated with hyperplasias and adenomas of the adrenal cortex and are linked to corticotropin-independent Cushing's syndrome. Altern
Catalog No
B0548
Reactivity
Human, Mouse, Rat, Pig
Source
Polyclonal, Rabbit,IgG
Modification
Unmodified/Total
Applications
WB, IHC, IF, ELISA
Dilution
WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
Store at -20°C/1 year
Other Name
PRKACA; PKACA; cAMP-dependent protein kinase catalytic subunit alpha; PKA C-alpha; PRKACB; cAMP-dependent protein kinase catalytic subunit beta; PKA C-beta; PRKACG; cAMP-dependent protein kinase catalytic subunit gamma; PKA C-gamma
Molecular Weight (Da or kDa)
Gene Name
PRKACA/PRKACB
Protein Name
cAMP-dependent protein kinase catalytic subunit alpha/beta
Human Gene ID
5566/5567
Human Swiss Prot No.
P17612 / P22694 / P22612
Immunogen
The antiserum was produced against synthesized peptide derived from human PKA alpha/beta CAT. AA range:166-215
Specificity
PKAα/β/γ cat Polyclonal Antibody detects endogenous levels of PKAα/β/γ cat protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Publications (6)
Effects and related mechanism of alpha-adrenergic receptor inhibitor phentolamine in a rabbit model of acute pulmonary embolism combined with shock

Author: Available in link provided

Date of Publication : Available in link provided

Pituitary miRNAs target GHRHR splice variants to regulate GH synthesis by mediating different intracellular signalling pathways. RNA Biology Rna Biol. 2020;17(12):1754-1766 WB Pig,Rat primary pituitary cell,GH3 cell

Author: Available in link provided

Date of Publication : Available in link provided

Regulation of the firing activity by PKA‐PKC‐Src family kinases in cultured neurons of hypothalamic arcuate nucleus. JOURNAL OF NEUROSCIENCE RESEARCH 2019 Aug 12 WB Rat 1:500 ARC neuron

Author: Available in link provided

Date of Publication : Available in link provided

miR-709 inhibits GHRP6 induced GH synthesis by targeting PRKCA in pituitary. MOLECULAR AND CELLULAR ENDOCRINOLOGY Mol Cell Endocrinol. 2020 Apr;506:110763 WB Rat GH3 cell

Author: Available in link provided

Date of Publication : Available in link provided

Lipolysis and thermogenesis in adipose tissues as new potential mechanisms for metabolic benefits of dietary fiber. NUTRITION 2016 Jun 02 WB Mouse white adipose tissue (WAT) ,brown adipose tissue

Author: Available in link provided

Date of Publication : Available in link provided

Effects and Mechanisms of Sciadonic Acid on Colonic Transit Function through Regulating 5-HT4/cAMP/PKA/AQP4 Signaling Pathway in STC Model Mice JOURNAL OF NUTRITIONAL BIOCHEMISTRY Zhuoli Yu WB Mouse colon tissue

Author: Available in link provided

Date of Publication : Available in link provided

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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