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Primary Antibodies
TGFβ RI Antibody
TGFβ RI Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: B1126
Reactivity:Human,Mouse,Rat
Applications:WB,IF,ELISA
Modification:Unmodified/Total
Source:Polyclonal,Rabbit,IgG
Storage and Stability:Store at -20°C/1 year

$205
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TGFβ RI Antibody

Immunofluorescence analysis of A549. 1,primary Antibody(red) was diluted at 1:200(4°C overnight). 2, Goat Anti Rabbit IgG (H&L) - Alexa Fluor 594 Secondary antibody was diluted at 1:1000(room temperature, 50min).3, Picture B: DAPI(blue) 10min.

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Product Details
Product Name
TGFβ RI Antibody
Description
The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008],
Catalog No
B1126
Reactivity
Human, Mouse, Rat
Source
Polyclonal, Rabbit,IgG
Modification
Unmodified/Total
Applications
WB, IF, ELISA
Dilution
WB 1:500 - 1:2000. ELISA: 1:20000. IF 1:100-300 Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
Store at -20°C/1 year
Other Name
TGFBR1; ALK5; SKR4; TGF-beta receptor type-1; TGFR-1; Activin A receptor type II-like protein kinase of 53kD; Activin receptor-like kinase 5; ALK-5; ALK5; Serine/threonine-protein kinase receptor R4; SKR4; TGF-beta type I receptor; Transfor
Molecular Weight (Da or kDa)
Gene Name
TGFBR1
Protein Name
TGF-beta receptor type-1
Human Gene ID
7046
Human Swiss Prot No.
P36897
Immunogen
The antiserum was produced against synthesized peptide derived from human TGF beta Receptor I. AA range:131-180
Specificity
TGFβ RI Polyclonal Antibody detects endogenous levels of TGFβ RI protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Publications (5)
M2 macrophage-mediated interleukin-4 signalling induces myofibroblast phenotype during the progression of benign prostatic hyperplasia. Cell Death & Disease Cell Death Dis. 2018 Jul;9(7):1-13 WB,IF Human 1:400 prostate tissue prostate fibroblasts

Author: Available in link provided

Date of Publication : Available in link provided

Tanshinone IIA mediates SMAD7-YAP interaction to inhibit liver cancer growth by inactivating the transforming growth factor beta signaling pathway. Aging-US Aging-Us. 2019 Nov 15; 11(21): 9719–9737 WB Human 1:2000 Bel-7404 cell, SMMC-7721 cell

Author: Available in link provided

Date of Publication : Available in link provided

Pan, Ming-Ming, et al. "Inhibition of TGF-β1/Smad signal pathway is involved in the effect of Cordyceps sinensis against renal fibrosis in 5/6 nephrectomy rats." Food and chemical toxicology 58 (2013): 487-494.

Author: Available in link provided

Date of Publication : Available in link provided

TrxR/Trx inhibitor butaselen ameliorates pulmonary fibrosis by suppressing NF-κB/TGF-β1/Smads signaling BIOMEDICINE & PHARMACOTHERAPY Yifan Chen WB Human 1:1000 HFL-1 cell

Author: Available in link provided

Date of Publication : Available in link provided

GDF-15 Inhibits ADP-Induced Human Platelet Aggregation through the GFRAL/RET Signaling Complex Biomolecules Baikang Xie WB Human 1:1000 platelets,erythrocytes,leukocytes

Author: Available in link provided

Date of Publication : Available in link provided

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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