SLP-76 Antibody (B8209) | Assay Biotech Inc.

SLP-76 Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: B8209

Reactivity:Human,Mouse,Rat

Applications:WB,IHC,IF,ELISA

Modification:Unmodified/Total

Source:Polyclonal,Rabbit,IgG

Storage and Stability:Store at -20°C/1 year

Size:

Price/Quantity $205

Quantity:

Datasheet

SDS

Lymphocyte Signaling

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SLP-76 Antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using SLP-76 Antibody. The picture on the right is blocked with the synthesized peptide.

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Lead Time

Antibodies 1-2 business day, ELISA kits 2-3 business day lead time

Telephone

408-747-0185

Fax

408-747-0145

order@assaybiotech.com

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Product Details

Product Name

SLP-76 Antibody

Description

SLP-76 was originally identified as a substrate of the ZAP-70 protein tyrosine kinase following T cell receptor (TCR) ligation in the leukemic T cell line Jurkat. The SLP-76 locus has been localized to human chromosome 5q33 and the gene structure has been partially characterized in mice. The human and murine cDNAs both encode 533 amino acid proteins that are 72% identical and comprised of three modular domains. The NH2-terminus contains an acidic region that includes a PEST domain and several tyrosine residues which are phosphorylated following TCR ligation. SLP-76 also contains a central proline-rich domain and a COOH-terminal SH2 domain. A number of additional proteins have been identified that associate with SLP-76 both constitutively and inducibly following receptor ligation, supporting the notion that SLP-76 functions as an adaptor or scaffold protein. Studies using SLP-76 deficient T c

Catalog No

B8209

Reactivity

Human, Mouse, Rat

Source

Polyclonal, Rabbit,IgG

Modification

Unmodified/Total

Applications

WB, IHC, IF, ELISA

Dilution

WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Storage and Stability

Store at -20°C/1 year

Other Name

LCP2; Lymphocyte cytosolic protein 2; SH2 domain-containing leukocyte protein of 76 kDa; SLP-76 tyrosine phosphoprotein; SLP76

Molecular Weight (Da or kDa)

Gene Name

LCP2

Protein Name

Lymphocyte cytosolic protein 2

Human Gene ID

3937

Human Swiss Prot No.

Q13094

Immunogen

The antiserum was produced against synthesized peptide derived from human SLP-76. AA range:94-143

Specificity

SLP-76 Polyclonal Antibody detects endogenous levels of SLP-76 protein.

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Catalog No: SA0002

HRP* Goat Anti Rabbit IgG(H+L)

Price/Quantity:
$50

Size:
100μL

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Catalog No: B8209

Reactivity:Human,Mouse,Rat

Applications:WB,IHC,IF,ELISA

Modification:Unmodified/Total

Source:Polyclonal,Rabbit,IgG

Storage and Stability:Store at -20°C/1 year

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