Sign In/Register 0

We use cookies, check our Privacy Policies.

> Products > Primary Antibodies > SREBP-1 Antibody

SREBP-1 Antibody

Overview Description
Datasheet SDS
Catalog No : C10578
  • Reactivity
    Human,Mouse,Rat
  • Applications
    WB,ELISA
  • Modification
    Unmodified/Total
  • Source
    Polyclonal Rabbit
  • Storage and Stability
    -20°C/1 year
  • Size
    50 μl
  • Price/Quantity
    $205
  • Quantity
Add to Cart
Details
  • Product Name
    SREBP-1 Antibody
  • Description
    This gene encodes a transcription factor that binds to the sterol regulatory element-1 (SRE1), which is a decamer flanking the low density lipoprotein receptor gene and some genes involved in sterol biosynthesis. The protein is synthesized as a precursor that is attached to the nuclear membrane and endoplasmic reticulum. Following cleavage, the mature protein translocates to the nucleus and activates transcription by binding to the SRE1. Sterols inhibit the cleavage of the precursor, and the mature nuclear form is rapidly catabolized, thereby reducing transcription. The protein is a member of the basic helix-loop-helix-leucine zipper (bHLH-Zip) transcription factor family. This gene is located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Mar 2016]
  • Catalog No
    C10578
  • Reactivity
    Human, Mouse, Rat
  • Applications
    WB, ELISA
  • Modification
    Unmodified/Total
  • Source
    Polyclonal Rabbit
  • Dilution
    WB 1:500-2000, ELISA 1:10000-20000
  • Purification
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration
    1 mg/ml
  • Storage and Stability
    -20°C/1 year
  • Other Name
    Sterol regulatory element-binding protein 1 (SREBP-1) (Class D basic helix-loop-helix protein 1) (bHLHd1) (Sterol regulatory element-binding transcription factor 1) [Cleaved into: Processed sterol regulatory element-binding protein 1]
  • Molecular Weight (Da)
  • Gene Name
    SREBF1 BHLHD1 SREBP1
  • Protein Name
    SREBP-1
  • Human Gene ID
    6720
  • Human Swiss Prot No.
    P36956
  • Immunogen
    Synthesized peptide derived from human SREBP-1. at AA range: 250-330
  • Specificity
    This antibody detects endogenous levels of SREBP-1
  • Formulation
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
dfsdfdfd
References: sdfdsfdsf
Abstract:

dsfdsf

View Publication
Application Data
Western Blot analysis of 1,mouse-liver 2,hela 3,mouse-brain cells using primary antibody diluted at 1:1000(4°C overnight). Secondary antibody:Goat Anti-rabbit IgG IRDye 800( diluted at 1:5000, 25°C, 1 hour)
Application Data
Chen, Kuikui, et al. "Investigation of the lipid-lowering mechanisms and active ingredients of Danhe granule on hyperlipidemia based on systems pharmacology." Frontiers in pharmacology 11 (2020): 528.
Publications

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
    © 2024 AssayBiotech. All Rights Reserved.
    Follow Us
    Terms of Use Privacy Policy