Description
The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and protein kinase superfamily involved in signal transduction pathways. This gene is closely linked to DRD2 gene (GeneID:1813) on chr 11, and a well studied restriction fragment length polymorphism (RFLP) designated TaqIA, was originally associated with the DRD2 gene, however, later was determined to be located in exon 8 of ANKK1 gene (PMIDs: 18621654, 15146457), where it causes a nonconservative amino acid substitution. It is not clear if this gene plays any role in neuropsychiatric disorders previously associated with Taq1A RFLP. [provided by RefSeq, Sep 2009]
Reactivity
Human, Rat, Mouse
Applications
WB, ELISA
Modification
Unmodified/Total
Source
Polyclonal Rabbit
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
-20°C/1 year
Other Name
ANKK1; PKK2; SGK288; Ankyrin repeat and protein kinase domain-containing protein 1; Protein kinase PKK2; Sugen kinase 288; SgK288; X-kinase
Molecular Weight (Da)
84632
Gene Name
ANKK1
Protein Name
Ankyrin repeat and protein kinase domain-containing protein 1
Human Gene ID
255239
Human Swiss Prot No.
Q8NFD2
Immunogen
The antiserum was produced against synthesized peptide derived from human ANKK1. AA range:321-370
Specificity
SgK288 Polyclonal Antibody detects endogenous levels of SgK288 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.