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Primary Antibodies
Btk (Phospho-Tyr223) Antibody
Btk (Phospho-Tyr223) Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: A0054
Reactivity:Human,Mouse,Rat
Applications:WB,ELISA
Modification:Phospho Specific
Source:Polyclonal Rabbit
Storage and Stability:-20°C/1 year

$205
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Btk (Phospho-Tyr223) Antibody

Western blot analysis of lysates from HeLa cells treated with Serum 10% 15', using BTK (Phospho-Tyr223) Antibody. The lane on the right is blocked with the phospho peptide.

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Product Details
Product Name
Btk (Phospho-Tyr223) Antibody
Description
The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2013]
Catalog No
A0054
Reactivity
Human, Mouse, Rat
Applications
WB, ELISA
Modification
Phospho Specific
Source
Polyclonal Rabbit
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
-20°C/1 year
Other Name
BTK; AGMX1; ATK; BPK; Tyrosine-protein kinase BTK; Agammaglobulinaemia tyrosine kinase; ATK; B-cell progenitor kinase; BPK; Bruton tyrosine kinase
Molecular Weight (Da)
76150
Gene Name
BTK
Protein Name
Tyrosine-protein kinase BTK
Human Gene ID
695
Human Swiss Prot No.
Q06187
Immunogen
The antiserum was produced against synthesized peptide derived from human BTK around the phosphorylation site of Tyr223. AA range:188-237
Specificity
Phospho-Btk (Y223) Polyclonal Antibody detects endogenous levels of Btk protein only when phosphorylated at Y223.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Publications (1)
Non-classical MHC I-E negatively regulates macrophage activation and Th17 cell development in NOD mice

Author: Yang, Chunhui, Guo, Nining, Liu, Jinhua, Yang, Juhao, Zhu, Kai, Xiao, Hui, Leng, Qibin

Date of Publication : 2015-08-07

Primary Antibodies

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    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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