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Primary Antibodies
p47-phox (Phospho-Ser370) Antibody
p47-phox (Phospho-Ser370) Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: A1171
Reactivity:Human,Mouse,Rat
Applications:WB,IHC-p,IF(paraffin section),ELISA
Modification:Phospho Specific
Source:Polyclonal Rabbit
Storage and Stability:-20°C/1 year

$205
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p47-phox (Phospho-Ser370) Antibody

Western blot analysis of p47 phox (Phospho-Ser370) Antibody. The lane on the right is blocked with the p47 phox (Phospho-Ser370) peptide.

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Product Details
Product Name
p47-phox (Phospho-Ser370) Antibody
Description
The protein encoded by this gene is a 47 kDa Cytosolic subunit of neutrophil NADPH oxidase. This oxidase is a multicomponent enzyme that is activated to produce superoxide anion. Mutations in this gene have been associated with chronic granulomatous disease. [provided by RefSeq, Jul 2008]
Catalog No
A1171
Reactivity
Human, Mouse, Rat
Applications
WB, IHC-p, IF(paraffin section), ELISA
Modification
Phospho Specific
Source
Polyclonal Rabbit
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
-20°C/1 year
Other Name
NCF1; NOXO2; SH3PXD1A; Neutrophil cytosol factor 1; NCF-1; 47 kDa autosomal chronic granulomatous disease protein; 47 kDa neutrophil oxidase factor; NCF-47K; Neutrophil NADPH oxidase factor 1; Nox organizer 2; Nox-organizing protein 2; SH3
Molecular Weight (Da)
44683
Gene Name
NCF1
Protein Name
Neutrophil cytosol factor 1
Human Gene ID
653361
Human Swiss Prot No.
P14598
Immunogen
The antiserum was produced against synthesized peptide derived from human p47 phox around the phosphorylation site of Ser370. AA range:341-390
Specificity
Phospho-p47-phox (S370) Polyclonal Antibody detects endogenous levels of p47-phox protein only when phosphorylated at S370.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Publications (4)
Molecular Mechanisms of N-Formyl-Methionyl-Leucyl-PhenylalanineInduced Superoxide Generation and Degranulation in Mouse Neutrophils: Phospholipase D Is Dispensable

Author: Takanobu Sato, Tsunaki Hongu, Megumi Sakamoto, Yuji Funakoshi, Yasunori Kanaho

Date of Publication : n/a

Molecular mechanisms of fMLP-induced superoxide generation and degranulation in mouse neutrophils: PLD is dispensable

Author: Takanobu Sato1, 2, Tsunaki Hongu1, 2, Megumi Sakamoto1, Yuji Funakoshi1 and Yasunori Kanaho

Date of Publication : n/a

TRPC3 positively regulates reactive oxygen species driving maladaptive cardiac remodeling

Author: Naoyuki Kitajima, Takuro Numaga-Tomita, Masahiko Watanabe, Takuya Kuroda, Akiyuki Nishimura, Kei Miyano, Satoshi Yasuda, Koichiro Kuwahara, Yoji Sato, Tomomi Ide, Lutz Birnbaumer, Hideki Sumimoto, Yasuo Mori & Motohiro Nishida

Date of Publication : n/a

Effect Augmented by Burkholderia C Activation of the NADPH Oxidase, an Defective Calcium-Dependent Protein Kinase Human Cystic Fibrosis Macrophages Hav

Author: Kaivon Assani, Chandra L. Shrestha, Frank Robledo-Avila, Murugesan V. Rajaram, Santiago Partida-Sanchez, Larry S. Schlesinger and Benjamin T. Kopp

Date of Publication : n/a

Primary Antibodies

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    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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