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Primary Antibodies
ERK 1/2 (Phospho-Thr202/Y204) Antibody
ERK 1/2 (Phospho-Thr202/Y204) Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: A8229
Reactivity:Human,Mouse,Rat
Applications:IF/ICC,WB,IHC-p,ELISA
Modification:Phospho Specific
Source:Polyclonal Rabbit
Storage and Stability:-20°C/1 year

$205
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ERK 1/2 (Phospho-Thr202/Y204) Antibody

Western Blot analysis of various cells using Phospho-ERK 1/2 (T202/Y204) Polyclonal Antibody

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Product Details
Product Name
ERK 1/2 (Phospho-Thr202/Y204) Antibody
Description
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described. [provided by RefSeq, Jul 2008]
Catalog No
A8229
Reactivity
Human, Mouse, Rat
Applications
IF/ICC, WB, IHC-p, ELISA
Modification
Phospho Specific
Source
Polyclonal Rabbit
Dilution
IF: 1:50-200 Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
-20°C/1 year
Other Name
MAPK3; ERK1; PRKM3; Mitogen-activated protein kinase 3; MAP kinase 3; MAPK 3; ERT2; Extracellular signal-regulated kinase 1; ERK-1; Insulin-stimulated MAP2 kinase; MAP kinase isoform p44; p44-MAPK; Microtubule-associated protein 2 kinase; p
Molecular Weight (Da)
43136
Gene Name
MAPK1/MAPK3
Protein Name
Mitogen-activated protein kinase 3
Human Gene ID
5595/5594
Human Swiss Prot No.
P27361/P28482
Immunogen
Synthesized phospho-peptide around the phosphorylation site of human ERK 1/2 (phospho Thr202/Y204)
Specificity
Phospho-ERK 1/2 (T202/Y204) Polyclonal Antibody detects endogenous levels of ERK 1/2 protein only when phosphorylated at T202 or Y204.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Publications (7)
Effect of cold stress on the MAPK pathway and lipidomics on muscle of Takifugu fasciatus

Author: Peng Chu, Tao Wang, Yi Ru Sun, Ming Xu Chu, Hong Yu Wang, Xiang Zheng, Shaowu Yin

Date of Publication : 2021-03-26

Circular RNA circNRIP1 promotes migration and invasion in cervical cancer by sponging miR-629-3p and regulating the PTP4A1/ERK1/2 pathway

Author: Li, Xinhui, Ma, Ningye, Zhang, Yao, Wei, Heng, Zhang, Huijie, Pang, Xiaoao, Li, Xiang, Wu, Dan, Wang, Dian, Yang, Zhuo, Zhang, Shulan

Date of Publication : 2020-05-26

Novel paeonol derivatives: Design, synthesis and anti-inflammatory activity in vitro and in vivo

Author: Yang Sheng Hu, Xu Han, Pei Jing Yu, Ming Ming Jiao, Xin Hua Liu, Jing Bo Shi

Date of Publication : 2020-03-08

Mesenchymal stem cell‑derived extracellular vesicles promote the in vitro proliferation and migration of breast cancer cells through the activation of the ERK pathway

Author: Xiaohe Zhou, Tao Li, Yufei Chen, Nannan Zhang, Pengli Wang, Yingying Liang, Melissa Long, Haoran Liu, Jian Mao, Qiuyan Liu, Xiaochun Sun, Huabiao Chen

Date of Publication : 2019-05-01

CXCL5, the upregulated chemokine in patients with uterine cervix cancer, in vivo and in vitro contributes to oncogenic potential of Hela uterine cervix cancer cells

Author: Xiaona Feng, Danfeng Zhang, Xinyi Li, Shuxia Ma, Chunbin Zhang, Jingtao Wang, Yue Li, Lichun Liang, Pengxia Zhang, Yikun Qu, Zeyu Zhang, Zhe Yang, Yu Xiang, Weili Zhang, Shuqiu Wang, Wenwu Shao, Weiqun Wang

Date of Publication : 2018-09-05

CTGF enhances resistance to 5-FU-mediating cell apoptosis through FAK/MEK/ERK signal pathway in colorectal cancer

Author: Kai Yang, Kai Gao, Gui Hu, Yanguang Wen, Changwei Lin, Xiaorong Li

Date of Publication : 2016-11-30

SCF/C-KIT signaling modulates tryptase expression in acute myeloid leukemia cells

Author: Jin, Jingchun, Li, Yan, Wang, Yue, Wang, Pingping, Wang, Yazhu

Date of Publication : 2014-05-08

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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