N-Shc Antibody (C18734) | Assay Biotech Inc.

N-Shc Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: C18734

Reactivity:Human,Mouse,Rat

Applications:IHC,IF,ELISA

Modification:Unmodified/Total

Source:Polyclonal,Rabbit,IgG

Storage and Stability:Store at -20°C/1 year

Size:

Price/Quantity $205

Quantity:

Datasheet

SDS

Signaling Intermediates

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N-Shc Antibody

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using SHC3 Antibody. The picture on the right is blocked with the synthesized peptide.

Delivery

Freight Charges

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Lead Time

Antibodies 1-2 business day, ELISA kits 2-3 business day lead time

Telephone

408-747-0185

Fax

408-747-0145

order@assaybiotech.com

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Product Details

Product Name

N-Shc Antibody

Description

function:Signaling adapter that couples activated growth factor receptors to signaling pathway in neurons. Involved in the signal transduction pathways of neurotrophin-activated Trk receptors in cortical neurons.,PTM:Tyrosine phosphorylated.,similarity:Contains 1 PID domain.,similarity:Contains 1 SH2 domain.,subunit:Interacts with the Trk receptors in a phosphotyrosine-dependent manner. Once activated, binds to GRB2. Interacts with activated EGF receptors.,tissue specificity:Mainly expressed in brain. Hardly detectable in other tissues, except in pancreas. Highly expressed in the cerebral cortex, frontal and temporal lobes, occipital pole, hippocampus, caudate nucleus and amygdala. Expressed at low level in the cerebellum, medulla and spinal cord.,

Catalog No

C18734

Reactivity

Human, Mouse, Rat

Source

Polyclonal, Rabbit,IgG

Modification

Unmodified/Total

Applications

IHC, IF, ELISA

Dilution

IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Storage and Stability

Store at -20°C/1 year

Other Name

SHC3; NSHC; SHCC; SHC-transforming protein 3; Neuronal Shc; N-Shc; Protein Rai; SHC-transforming protein C; Src homology 2 domain-containing-transforming protein C3; SH2 domain protein C3

Molecular Weight (Da or kDa)

Gene Name

SHC3

Protein Name

SHC-transforming protein 3

Human Gene ID

53358

Human Swiss Prot No.

Q92529

Immunogen

The antiserum was produced against synthesized peptide derived from human SHC3. AA range:291-340

Specificity