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Sgo2 Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: C18741
Reactivity:Human,Rat,Mouse
Applications:IHC,IF,ELISA
Modification:Unmodified/Total
Source:Polyclonal,Rabbit,IgG
Storage and Stability:Store at -20°C/1 year

$205
Product Details
Product Name
Sgo2 Antibody
Description
function:During meiosis, protects centromeric cohesion complexes until metaphase II/anaphase II transition, preventing premature release of meiosis-specific REC8 cohesin complexes from anaphase I centromeres. Is thus essential for an accurate gametogenesis (By similarity). May act by targeting PPP2CA to centromeres, thus leading to cohesin dephosphorylation.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Belongs to the shugoshin family.,subcellular location:In Hela cells, localizes at centromeres throughout prophase until metaphase and disappears at anaphase.,subunit:Directly interacts with PPP2CA.,
Catalog No
C18741
Reactivity
Human, Rat, Mouse
Source
Polyclonal, Rabbit,IgG
Modification
Unmodified/Total
Applications
IHC, IF, ELISA
Dilution
IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
Store at -20°C/1 year
Other Name
SGOL2; Shugoshin-like 2; Shugoshin-2; Sgo2; Tripin
Molecular Weight (Da or kDa)
145kD
Gene Name
SGOL2
Protein Name
Shugoshin-like 2
Human Gene ID
151246
Human Swiss Prot No.
Q562F6
Immunogen
The antiserum was produced against synthesized peptide derived from human SGOL2. AA range:681-730
Specificity
Sgo2 Polyclonal Antibody detects endogenous levels of Sgo2 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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