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Primary Antibodies
VEGFR2 Antibody
VEGFR2 Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: C47670
Reactivity:Human
Applications:IF,WB,IHC,ELISA
Modification:Unmodified/Total
Source:Polyclonal,Rabbit,IgG
Storage and Stability:Store at -20°C/1 year

$205
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VEGFR2 Antibody

Immunohistochemical analysis of paraffin-embedded human-breast-cancer, antibody was diluted at 1:200

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Product Details
Product Name
VEGFR2 Antibody
Description
Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells.This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq, May 2009],
Catalog No
C47670
Reactivity
Human
Source
Polyclonal, Rabbit,IgG
Modification
Unmodified/Total
Applications
IF, WB, IHC, ELISA
Dilution
IF 1:50-200 WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000. Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
Store at -20°C/1 year
Other Name
Vascular endothelial growth factor receptor 2 (VEGFR-2; EC 2.7.10.1; Fetal liver kinase 1; FLK-1; Kinase insert domain receptor; KDR; Protein-tyrosine kinase receptor flk-1; CD antigen CD309)
Molecular Weight (Da or kDa)
152kD
Gene Name
KDR FLK1 VEGFR2
Protein Name
VEGFR2
Human Gene ID
3791
Human Swiss Prot No.
P35968
Immunogen
Synthetic peptide from human protein at AA range: 1268-1341
Specificity
The antibody detects endogenous VEGFR2
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Publications (5)
Marine bromophenol bis(2,3-dibromo-4,5-dihydroxybenzyl) ether, represses angiogenesis in HUVEC cells and in zebrafish embryos via inhibiting the VEGF signal systems. BIOMEDICINE & PHARMACOTHERAPY 2015 Sep 07 WB Human HUVECs

Author: Available in link provided

Date of Publication : Available in link provided

Marine bromophenol bis (2, 3-dibromo-4, 5-dihydroxybenzyl) ether, represses angiogenesis in HUVEC cells and in zebrafish embryos via inhibiting the VEGF signal systems." Biomedicine & Pharmacotherapy 75 (2015): 58-66.

Author: Available in link provided

Date of Publication : Available in link provided

Li, Na, et al. "Asparaginyl endopeptidase may promote liver sinusoidal endothelial cell angiogenesis via PI3K/Akt pathway." Revista espanola de enfermedades digestivas: organo oficial de la Sociedad Espanola de Patologia Digestiva111 (2018).

Author: Available in link provided

Date of Publication : Available in link provided

Acute hypoxia promotes the liver angiogenesis of largemouth bass (Micropterus salmoides) by HIF - Dependent pathway FISH & SHELLFISH IMMUNOLOGY Liulan Zhao WB,IHC Fish

Author: Available in link provided

Date of Publication : Available in link provided

Gualou Guizhi decoction promotes therapeutic angiogenesis via the miR210/HIF/VEGF pathway in vivo and in vitro. Lihong Nan WB Rat,Human Ischemic brain tissue Human umbilical vein endothelial cell (HUVEC)

Author: Available in link provided

Date of Publication : Available in link provided

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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