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Primary Antibodies
IL-6 Antibody
IL-6 Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: C30006
Reactivity:Human
Applications:WB,IHC,IF,ELISA
Modification:Unmodified/Total
Source:Polyclonal,Rabbit,IgG
Storage and Stability:Store at -20°C/1 year

$205
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IL-6 Antibody

Immunofluorescence analysis of A549. 1,primary Antibody(red) was diluted at 1:200(4°C overnight). 2, Goat Anti Rabbit IgG (H&L) - Alexa Fluor 594 Secondary antibody was diluted at 1:1000(room temperature, 50min).3, Picture B: DAPI(blue) 10min.

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Product Details
Product Name
IL-6 Antibody
Description
This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015],
Catalog No
C30006
Reactivity
Human
Source
Polyclonal, Rabbit,IgG
Modification
Unmodified/Total
Applications
WB, IHC, IF, ELISA
Dilution
WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000. IF 1:100-300 Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
Store at -20°C/1 year
Other Name
IL6; IFNB2; Interleukin-6; IL-6; B-cell stimulatory factor 2; BSF-2; CTL differentiation factor; CDF; Hybridoma growth factor; Interferon beta-2; IFN-beta-2
Molecular Weight (Da or kDa)
Gene Name
IL6
Protein Name
Interleukin-6
Human Gene ID
3569
Human Swiss Prot No.
P05231
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human IL6. AA range:131-180
Specificity
IL-6 Polyclonal Antibody detects endogenous levels of IL-6 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Publications (25)
Maresin1 ameliorates ventricular remodelling and arrhythmia in mice models of myocardial infarction via NRF2/HO-1 and TLR4/NF-kB signalling

Author: Available in link provided

Date of Publication : Available in link provided

Dual Inhibition of H3K9me2 and H3K27me3 Promotes Tumor Cell Senescence without Triggering the Secretion of SASP. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES2022 Jan;23(7):3911. Human MDA-MB-231 cell

Author: Available in link provided

Date of Publication : Available in link provided

The Long-Noncoding RNA TUG1 Regulates Oxygen-Induced Retinal Neovascularization in Mice via MiR-299 Invest Ophth Vis Sci. 2022 Jan;63(1):37-37. WB,IF,IHC Mouse 1:1000,1:200 retina

Author: Available in link provided

Date of Publication : Available in link provided

Arginine hypomethylation-mediated proteasomal degradation of histone H4—an early biomarker of cellular senescence. CELL DEATH AND DIFFERENTIATION Cell Death Differ. 2020 May;27(9):2697-2709 WB Human IMR90 cell

Author: Available in link provided

Date of Publication : Available in link provided

Human Novel MicroRNA Seq-915_x4024 in Keratinocytes Contributes to Skin Regeneration by Suppressing Scar Formation. Molecular Therapy-Nucleic Acids Mol Ther-Nucl Acids. 2019 Mar;14:410 WB Human HaCaT cell

Author: Available in link provided

Date of Publication : Available in link provided

Maternally expressed gene 3 regulates retinal neovascularization in retinopathy of prematurity. Neural Regeneration Research Neural Regen Res. 2022 Jun; 17(6): 1364–1368 WB Mouse 1:1000 Retina

Author: Available in link provided

Date of Publication : Available in link provided

Lipopolysaccharide Promotes Inflammatory Response via Enhancing IFIT1 Expression in Human Umbilical Vein Endothelial Cells. DNA AND CELL BIOLOGY Dna Cell Biol. 2020 Jul;39(7):1274-1281 WB Human HUVECs

Author: Available in link provided

Date of Publication : Available in link provided

The potentially protective role of ATP-binding cassette transporters in preeclampsia via Nrf2. Pregnancy Hypertension-An International Journal of Womens Cardiovascular Health WB Human placental

Author: Available in link provided

Date of Publication : Available in link provided

Jiang, Kang-feng, et al. "Polydatin ameliorates Staphylococcus aureus-induced mastitis in mice via inhibiting TLR2-mediated activation of the p38 MAPK/NF-κB pathway." Acta Pharmacologica Sinica 38.2 (2017): 211.

Author: Available in link provided

Date of Publication : Available in link provided

Hui, Zhi, and Zhe Li. "Continuous veno-venous hemofiltration for septic shock." INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE 10.10 (2017): 14983-14988.

Author: Available in link provided

Date of Publication : Available in link provided

Tubeimoside I Ameliorates Doxorubicin-Induced Cardiotoxicity by Upregulating SIRT3 Oxidative Medicine and Cellular Longevity Congxin Huang WB Mouse heart tissue H9c2 cells

Author: Available in link provided

Date of Publication : Available in link provided

Mannosylated polydopamine nanoparticles alleviate radiation- induced pulmonary fibrosis by targeting M2 macrophages and inhibiting the TGF-β1/Smad3 signaling pathway. Yuhui Hao WB Mouse lung tissue

Author: Available in link provided

Date of Publication : Available in link provided

High Hepcidin Levels Promote Abnormal Iron Metabolism and Ferroptosis in Chronic Atrophic Gastritis. Biomedicines Qian Yang IHC,WB Rat gastric tissue

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Date of Publication : Available in link provided

Clostridium butyricum MIYAIRI 588 alleviates periodontal bone loss in mice with diabetes mellitus. ANNALS OF THE NEW YORK ACADEMY OF SCIENCES Jinlin Song WB Mouse Bone marrow-derived macrophages (BMDMs)

Author: Available in link provided

Date of Publication : Available in link provided

Production of recombinant human long-acting IL-18 binding protein: inhibitory effect on ulcerative colitis in mice. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY Xiao Yechen WB Mouse colonic tissues

Author: Available in link provided

Date of Publication : Available in link provided

AAV2-antiVEGFscFv gene therapy for retinal neovascularization. Molecular Therapy-Methods & Clinical Development Guangzuo Luo IHC Mouse eyes

Author: Available in link provided

Date of Publication : Available in link provided

Blocking brown adipocyte β3-adrenoceptor attenuates blood-spinal cord barrier impairment and chronic postsurgical pain in a rat model of preoperative stress INTERNATIONAL IMMUNOPHARMACOLOGY Jixiang Zhu IHC Rat 1:100 brown adipose tissues (BAT)

Author: Available in link provided

Date of Publication : Available in link provided

Inhibitor PF-04691502 works as a senolytic to regulate cellular senescence EXPERIMENTAL GERONTOLOGY Ziqiang Fan WB Mouse 1:1000 NIH-3T3 cell

Author: Available in link provided

Date of Publication : Available in link provided

Danshensu methyl ester attenuated LPS-induced acute lung injury by inhibiting TLR4/NF-κB pathway RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY Xuejia Han WB Mouse 1:1000 lung tissue RAW264.7 cell

Author: Available in link provided

Date of Publication : Available in link provided

Resveratrol regulates Thoc5 to improve maternal immune activation-induced autism-like behaviors in adult mouse offspring JOURNAL OF NUTRITIONAL BIOCHEMISTRY Xin Zeng WB Human 1:1000 placenta tissue, fetal brain tissue, cerebral corte tissue

Author: Available in link provided

Date of Publication : Available in link provided

The inhibitory effect and mechanisms of Diwu Yanggan on hepatic precancerous lesions in a 2-AAF/PH rat model Journal of Functional Foods Weidong Xu WB Rat liver tissue

Author: Available in link provided

Date of Publication : Available in link provided

Targeted lung therapy with rosmarinic acid encapsulated in PLGA microspheres for radiation-induced pulmonary fibrosis JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY Yonglai Chen IHC Mouse 1:200 Lung tissue

Author: Available in link provided

Date of Publication : Available in link provided

Exploring the effect of Clostridium butyricum on lung injury associated with acute pancreatitis in mice by combined 16S rRNA and metabolomics analysis ANAEROBE Jiaxin Liu IHC Mouse 1:400 pancreatic tissue,lung tissue

Author: Available in link provided

Date of Publication : Available in link provided

Renewable Electroconductive Hydrogels for Accelerated Diabetic Wound Healing and Motion Monitoring BIOMACROMOLECULES Xiao Qian Hu IF Rat skin tissue

Author: Available in link provided

Date of Publication : Available in link provided

Macrophage WNK1 senses intracellular hypo-chlorine to regulate vulnerability to sepsis attack during hypochloremia INTERNATIONAL IMMUNOPHARMACOLOGY Tianyue Yin WB Mouse bone marrow-derived macrophages (BMDMs),Raw264.7 cell

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Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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