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Primary Antibodies
SOCS-3 Antibody
SOCS-3 Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: C30266
Reactivity:Human,Mouse,Rat
Applications:WB,IHC,IF
Modification:Unmodified/Total
Source:Polyclonal,Rabbit,IgG
Storage and Stability:Store at -20°C/1 year

$205
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SOCS-3 Antibody

Immunohistochemical analysis of paraffin-embedded human-lung-cancer, antibody was diluted at 1:200

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Product Details
Product Name
SOCS-3 Antibody
Description
This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma.The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development. [provided by RefSeq, Jul 2008],
Catalog No
C30266
Reactivity
Human, Mouse, Rat
Source
Polyclonal, Rabbit,IgG
Modification
Unmodified/Total
Applications
WB, IHC, IF
Dilution
WB 1:500 - 1:2000.IHC:1:50-300.. IF 1:50-200
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
Store at -20°C/1 year
Other Name
Suppressor of cytokine signaling 3 (SOCS-3; Cytokine-inducible SH2 protein 3; CIS-3; STAT-induced STAT inhibitor 3; SSI-3)
Molecular Weight (Da or kDa)
25kD
Gene Name
SOCS3 CIS3 SSI3
Protein Name
Suppressor of cytokine signaling 3 (SOCS-3) (Cytokine-inducible SH2 protein 3) (CIS-3) (STAT-induced STAT inhibitor 3) (SSI-3)
Human Gene ID
9021
Human Swiss Prot No.
O14543
Immunogen
Synthetic peptide from human protein at AA range: 20-70
Specificity
The antibody detects endogenous SOCS-3
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Publications (1)
Lack of SOCS3 increases LPS-induced murine acute lung injury through modulation of Ly6C(+) macrophages. RESPIRATORY RESEARCH Resp Res. 2017 Dec;18(1):1-14 WB Mouse 1:500 bone marrow-derived macrophages (BMDMs)

Author: Available in link provided

Date of Publication : Available in link provided

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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