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> Products > Primary Antibodies > Cytokeratin 8 Antibody

Cytokeratin 8 Antibody

Overview Description
Datasheet SDS
   Structural Proteins   
Catalog No : D12135N
  • Reactivity
    Human,Rat,Mouse
  • Applications
    WB,IHC-p,IF(paraffin section),ELISA
  • Modification
    Unmodified/Total
  • Source
    Polyclonal Rabbit
  • Storage and Stability
    -20°C/1 year
  • Size
    50 μl
  • Price/Quantity
    $205
  • Quantity
Add to Cart
Details
  • Product Name
    Cytokeratin 8 Antibody
  • Description
    keratin 8(KRT8) Homo sapiens This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the Cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]
  • Catalog No
    D12135N
  • Reactivity
    Human, Rat, Mouse
  • Applications
    WB, IHC-p, IF(paraffin section), ELISA
  • Modification
    Unmodified/Total
  • Source
    Polyclonal Rabbit
  • Dilution
    Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.
  • Purification
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration
    1 mg/ml
  • Storage and Stability
    -20°C/1 year
  • Other Name
    KRT8; CYK8; Keratin, type II cytoskeletal 8; Cytokeratin-8; CK-8; Keratin-8; K8; Type-II keratin Kb8
  • Molecular Weight (Da)
    53573
  • Gene Name
    KRT8
  • Protein Name
    Keratin type II cytoskeletal 8
  • Human Gene ID
    3856
  • Human Swiss Prot No.
    P05787
  • Immunogen
    The antiserum was produced against synthesized peptide derived from human K8 around the non-acetylation site of Lys483. AA range:434-483
  • Specificity
    Cytokeratin 8 Polyclonal Antibody detects endogenous levels of Cytokeratin 8 protein.
  • Formulation
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Application Data
Western blot analysis of extracts from A549 cells, using K8 (Ab-483) Antibody.
Application Data
Immunohistochemical analysis of paraffin-embedded human-kidney, antibody was diluted at 1:100
Application Data
Immunohistochemical analysis of paraffin-embedded human-kidney, antibody was diluted at 1:100
Application Data
Immunohistochemical analysis of paraffin-embedded human-kidney, antibody was diluted at 1:100
Application Data
Immunohistochemical analysis of paraffin-embedded human-colon, antibody was diluted at 1:100
Application Data
Immunohistochemical analysis of paraffin-embedded human-colon, antibody was diluted at 1:100
Application Data
Western Blot analysis of A549 cells using Cytokeratin 8 Polyclonal Antibody. Secondary antibody(catalogNo.:SA0002) was diluted at 1:20000

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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