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Ku-80Antibody

Catalog No : D12146N
  • Reactivity
    Human,Rat,Mouse
  • Applications
    IHC-p,IF(paraffin section),WB
  • Modification
    Unmodified/Total
  • Source
    Polyclonal Rabbit
  • Storage and Stability
    -20°C/1 year
  • Size
    50 μl
  • Price/Quantity
    $205
  • Quantity
Details
  • Product Name
    Ku-80Antibody
  • Description
    The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008]
  • Catalog No
    D12146N
  • Reactivity
    Human, Rat, Mouse
  • Applications
    IHC-p, IF(paraffin section), WB
  • Modification
    Unmodified/Total
  • Source
    Polyclonal Rabbit
  • Dilution
    IHC-p 1:50-200, WB 1:500-2000
  • Purification
    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
  • Concentration
    1 mg/ml
  • Storage and Stability
    -20°C/1 year
  • Other Name
    X-ray repair cross-complementing protein 5 (EC 3.6.4.-) (86 kDa subunit of Ku antigen) (ATP-dependent DNA helicase 2 subunit 2) (ATP-dependent DNA helicase II 80 kDa subunit) (CTC box-binding factor 85 kDa subunit) (CTC85) (CTCBF) (DNA repair protein XRCC5) (Ku80) (Ku86) (Lupus Ku autoantigen protein p86) (Nuclear factor IV) (Thyroid-lupus autoantigen) (TLAA) (X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining))
  • Molecular Weight (Da)
  • Gene Name
    XRCC5 G22P2
  • Protein Name
    Ku-80
  • Human Gene ID
    7520
  • Human Swiss Prot No.
    P13010
  • Immunogen
    Synthesized peptide derived from human Ku-80
  • Specificity
    This antibody detects endogenous levels of human Ku-80
  • Formulation
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
No results found.