FAS-L Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: C30517

Reactivity:Human,Rat,Mouse

Applications:IHC,IF,ELISA

Modification:Unmodified/Total

Source:Polyclonal,Rabbit,IgG

Storage and Stability:Store at -20°C/1 year

Size:

Price/Quantity $205

Quantity:

Datasheet

SDS

Tumor Suppressors/Apoptosis

Buy One Get One

FAS-L Antibody

Immunohistochemical analysis of paraffin-embedded Human-colon-cancer, antibody was diluted at 1:100

Delivery

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Lead Time

Antibodies 1-2 business day, ELISA kits 2-3 business day lead time

Telephone

408-747-0185

Fax

408-747-0145

order@assaybiotech.com

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Product Details

Product Name

FAS-L Antibody

Description

This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE). Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2014],

Catalog No

C30517

Reactivity

Human, Rat, Mouse

Source

Polyclonal, Rabbit,IgG

Modification

Unmodified/Total

Applications

IHC, IF, ELISA

Dilution

IHC 1:50-200, ELISA 1:10000-20000. IF 1:50-200

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Storage and Stability

Store at -20°C/1 year

Other Name

Tumor necrosis factor ligand superfamily member 6 (Apoptosis antigen ligand; APTL; CD95 ligand; CD95-L; Fas antigen ligand; Fas ligand; FasL; CD antigen CD178) [Cleaved into: Tumor necrosis factor ligand superfamily member 6, membrane form; Tumor necrosis factor ligand superfamily member 6, soluble form (Receptor-binding FasL ectodomain; Soluble Fas ligand; sFasL); ADAM10-processed FasL form (APL); FasL intracellular domain (FasL ICD; SPPL2A-processed FasL form; SPA)]

Molecular Weight (Da or kDa)

Gene Name

FASLG APT1LG1 CD95L FASL TNFSF6

Protein Name

Tumor necrosis factor ligand superfamily member 6 (Apoptosis antigen ligand) (APTL) (CD95 ligand) (CD95-L) (Fas antigen ligand) (Fas ligand) (FasL) (CD antigen CD178) [Cleaved into: Tumor necrosis factor ligand superfamily member 6, membrane formTumor necrosis factor ligand superfamily member 6, soluble form (Receptor-binding FasL ectodomain) (Soluble Fas ligand) (sFasL)ADAM10-processed FasL form (APL)FasL intracellular domain (FasL ICD) (SPPL2A-processed FasL form) (SPA)]

Human Gene ID

356

Human Swiss Prot No.

P48023

Immunogen

Synthetic peptide from human protein at AA range: 121-170

Specificity

The antibody detects endogenous FAS-L

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.