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β-Catenin Antibody

Catalog No : C40034
  • Reactivity
    Mouse,Rat
  • Applications
    WB
  • Modification
    Unmodified/Total
  • Source
    Polyclonal Rabbit
  • Storage and Stability
    -20°C/1 year
  • Size
    50 μl
  • Price/Quantity
    $205
  • Quantity
Details
  • Product Name
    β-Catenin Antibody
  • Description
    The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016]
  • Catalog No
    C40034
  • Reactivity
    Mouse, Rat
  • Applications
    WB
  • Modification
    Unmodified/Total
  • Source
    Polyclonal Rabbit
  • Dilution
    WB: 1:2000-4000
  • Purification
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration
    1 mg/ml
  • Storage and Stability
    -20°C/1 year
  • Other Name
    CTNNB1; CTNNB; OK/SW-cl.35; Catenin beta-1; Beta-catenin; YM3345
  • Molecular Weight (Da)
    85497
  • Gene Name
    CTNNB1
  • Protein Name
    Catenin beta-1
  • Human Gene ID
    1499
  • Human Swiss Prot No.
    P35222
  • Immunogen
    Recombinant Protein of Catenin beta-1
  • Specificity
    The antibody detects endogenous β-Catenin protein.
  • Formulation
    PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
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