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β-Catenin Antibody
β-Catenin Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: C40034
Reactivity:Mouse,Rat
Applications:WB
Modification:Unmodified/Total
Source:Polyclonal Rabbit
Storage and Stability:-20°C/1 year

$205
Product Details
Product Name
β-Catenin Antibody
Description
The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016]
Catalog No
C40034
Reactivity
Mouse, Rat
Applications
WB
Modification
Unmodified/Total
Source
Polyclonal Rabbit
Dilution
WB: 1:2000-4000
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
-20°C/1 year
Other Name
CTNNB1; CTNNB; OK/SW-cl.35; Catenin beta-1; Beta-catenin; YM3345
Molecular Weight (Da)
85497
Gene Name
CTNNB1
Protein Name
Catenin beta-1
Human Gene ID
1499
Human Swiss Prot No.
P35222
Immunogen
Recombinant Protein of Catenin beta-1
Specificity
The antibody detects endogenous β-Catenin protein.
Formulation
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
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Publications (6)