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Primary Antibodies
GSDMD n-ternal Antibody
GSDMD n-ternal Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: C40206
Reactivity:Human,Mouse,Rat
Applications:IF,WB,IHC
Modification:Unmodified/Total
Source:Polyclonal,Rabbit,IgG
Storage and Stability:Store at -20°C/1 year

$150
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GSDMD n-ternal Antibody

Immunofluorescence analysis of un-treated (left) A549 and UV treated(right) A549 cell. 1,primary Antibody was diluted at 1:200(4°C overnight). 2, Goat Anti Rabbit IgG (H&L) - Alexa Fluor 594 Secondary antibody was diluted at 1:1000(room temperature, 50min).3, Picture B: DAPI(blue) 10min.

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Product Details
Product Name
GSDMD n-ternal Antibody
Description
Catalog No
C40206
Reactivity
Human, Mouse, Rat
Source
Polyclonal, Rabbit,IgG
Modification
Unmodified/Total
Applications
IF, WB, IHC
Dilution
IF 1:50-200 WB 1:1000-3000 IHC 1:50-300
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
Store at -20°C/1 year
Other Name
Molecular Weight (Da or kDa)
Gene Name
GSDMD
Protein Name
Gasdermin domain-containing protein 1,Gasdermin-D,GSDMD,GSDMD-CT,GSDMD-NT,GSDMD_HUMAN
Human Gene ID
Human Swiss Prot No.
P57764
Immunogen
Synthesized peptide derived from human GSDMD. AA range:1-100
Specificity
The antibody detects endogenous full lenth and n-ternal fragment of gsdmd protein,
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
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Publications (13)
Reduced hydrogen sulfide production contributes to adrenal insufficiency induced by hypoxia via modulation of NLRP3 inflammasome activation REDOX REPORT Changnan Wang WB Mouse adrenal glands

Author: Available in link provided

Date of Publication : Available in link provided

IL-37 alleviates TNF-α-induced pyroptosis of rheumatoid arthritis fibroblast-like synoviocytes by inhibiting the NF-κB/GSDMD signaling pathway IMMUNOBIOLOGY Qiang Shu IHC Human synovial tissue

Author: Available in link provided

Date of Publication : Available in link provided

Hypoxic preconditioned mesenchymal stem cells ameliorate rat brain injury after cardiopulmonary resuscitation by suppressing neuronal pyroptosis. Feng Chen WB Rat cortical tissue

Author: Available in link provided

Date of Publication : Available in link provided

Targeting the mechanism of IRF3 in sepsis-associated acute kidney injury via the Hippo pathway. Xingui Dai WB Human HK-2 cell

Author: Available in link provided

Date of Publication : Available in link provided

A novel drug combination of Tofacitinib and Iguratimod alleviates rheumatoid arthritis and secondary osteoporosis. INTERNATIONAL IMMUNOPHARMACOLOGY Qiang Shu IHC Rat 1:100 Synovial tissue,bone tissue

Author: Available in link provided

Date of Publication : Available in link provided

Cathepsin B aggravates atherosclerosis in ApoE-deficient mice by modulating vascular smooth muscle cell pyroptosis through NF-κB / NLRP3 signaling pathway PLoS One Hui Li IHC,WB Mouse 1:200 aorta tissue vascular smooth muscle cells (VSMCs)

Author: Available in link provided

Date of Publication : Available in link provided

Maresin-1 ameliorates hypertensive vascular remodeling through its receptor LGR6 MedComm Zheng Yin WB Rat rat aortic smooth muscle cells (RASMCs)

Author: Available in link provided

Date of Publication : Available in link provided

Blocking CIRP protects against acute pancreatitis by improving mitochondrial function and suppressing pyroptosis in acinar cells Cell Death Discovery Liu Wuming WB,IHC Mouse,Rat 1:1000 pancreatic tissue AR42J cell

Author: Available in link provided

Date of Publication : Available in link provided

AMPK signaling pathway regulated the expression of the ApoA1 gene via the transcription factor Egr1 during G. parasuis stimulation VETERINARY MICROBIOLOGY Yanling He WB Pig lung tissue

Author: Available in link provided

Date of Publication : Available in link provided

Ethyl pyruvate alleviates NLRP3/Caspase-1/GSDMD-mediated neuronal pyroptosis in neonatal rats with hypoxic–ischemic brain damage INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE Sha Sha WB Rat,Mouse 1:1000 hippocampal tissue HT22 cell

Author: Available in link provided

Date of Publication : Available in link provided

Targeting TANK-binding kinase 1 attenuates painful diabetic neuropathy via inhibiting microglia pyroptosis Cell Communication and Signaling Liao Qinming WB,IF Mouse spinal cord tissue

Author: Available in link provided

Date of Publication : Available in link provided

Molecular mechanism of HDAC6-mediated pyroptosis in neurological function recovery after cardiopulmonary resuscitation in rats BRAIN RESEARCH Chunyan Chen WB Rat 1:1000 brain tissue

Author: Available in link provided

Date of Publication : Available in link provided

The antidepressant effect of Shexiang Baoxin Pills on myocardial infarction rats with depression may be achieved through the inhibition of the NLRP3 inflammasome pathway Brain and Behavior Yue Wang WB,IF Rat 1:1000,1:100 brain tissue

Author: Available in link provided

Date of Publication : Available in link provided

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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