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Primary Antibodies
VEGF-A Antibody
VEGF-A Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: R12-2407
Reactivity:Human,Mouse,Rat,Pig,Rabbit
Applications:WB,IF,IHC,ELISA
Modification:Unmodified/Total
Source:Polyclonal,Rabbit,IgG
Storage and Stability:Store at -20°C/1 year

$205
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VEGF-A Antibody

Immunofluorescence analysis of mouse-kidney tissue. 1,VEGF-A Polyclonal Antibody(red) was diluted at 1:200(4°C,overnight). 2, Cy3 labled Secondary antibody was diluted at 1:300(room temperature, 50min).3, Picture B: DAPI(blue) 10min. Picture A:Target. Picture B: DAPI. Picture C: merge of A+B

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Product Details
Product Name
VEGF-A Antibody
Description
This gene is a member of the PDGF/VEGF growth factor family. It encodes a heparin-binding protein, which exists as a disulfide-linked homodimer. This growth factor induces proliferation and migration of vascular endothelial cells, and is essential for both physiological and pathological angiogenesis. Disruption of this gene in mice resulted in abnormal embryonic blood vessel formation. This gene is upregulated in many known tumors and its expression is correlated with tumor stage and progression. Elevated levels of this protein are found in patients with POEMS syndrome, also known as Crow-Fukase syndrome. Allelic variants of this gene have been associated with microvascular complications of diabetes 1 (MVCD1) and atherosclerosis. Alternatively spliced transcript variants encoding different isoforms have been described. There is also evidence for alternative translation initiation fro
Catalog No
R12-2407
Reactivity
Human, Mouse, Rat, Pig, Rabbit
Source
Polyclonal, Rabbit,IgG
Modification
Unmodified/Total
Applications
WB, IF, IHC, ELISA
Dilution
WB 1:500 - 1:2000.IF 1:50-200 IHC 1:100 - 1:300. ELISA: 1:10000. Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
Store at -20°C/1 year
Other Name
VEGFA; VEGF; Vascular endothelial growth factor A; VEGF-A; Vascular permeability factor; VPF
Molecular Weight (Da or kDa)
Gene Name
VEGFA
Protein Name
Vascular endothelial growth factor A
Human Gene ID
7422
Human Swiss Prot No.
P15692
Immunogen
The antiserum was produced against synthesized peptide derived from human VEGF-A. AA range:110-159
Specificity
VEGF-A Polyclonal Antibody detects endogenous levels of VEGF-A protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Publications (14)
Efficacy of Shexiang Tongxin Dropping Pills in a Swine Model of Coronary Slow Flow WB Pig 1:500 left ventricular apex/

Author: Available in link provided

Date of Publication : Available in link provided

Interleukin-35 inhibits angiogenesis through T helper17/ Interleukin-17 related signaling pathways in IL-1β-stimulated SW1353 cells. MOLECULAR IMMUNOLOGY2022 Jul;147:71. Human SW1353 cell

Author: Available in link provided

Date of Publication : Available in link provided

Recombinant human endostatin reduces hypertrophic scar formation in rabbit ear model through down-regulation of VEGF and TIMP-1. African Health Sciences Afr Health Sci. 2016 Jul;16(2):542-553 WB Rabbit wound area tissue

Author: Available in link provided

Date of Publication : Available in link provided

CXCR7/p-ERK-Signaling Is a Novel Target for Therapeutic Vasculogenesis in Patients with Coronary Artery Disease. PLoS One 2016 Sep 09 WB Human 1:500 EOCs

Author: Available in link provided

Date of Publication : Available in link provided

Inhibin B suppresses anoikis resistance and migration through the transforming growth factor‐β signaling pathway in nasopharyngeal carcinoma. CANCER SCIENCE Cancer Sci. 2018 Nov;109(11):3416-3427 WB Human HNE1 cell， 5-8F cell

Author: Available in link provided

Date of Publication : Available in link provided

Endothelin-1 Activates the Notch Signaling Pathway and Promotes Tumorigenesis in Giant Cell Tumor of the Spine. SPINE Spine. 2019 Sep;44(17):E1000-E1009 WB Human 1:500 giant cell tumor (GCT) tissue

Author: Available in link provided

Date of Publication : Available in link provided

SENP6-Mediated deSUMOylation of VEGFR2 Enhances Its Cell Membrane Transport in Angiogenesis INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Xiaohua Guo WB Human human umbilical vein endothelial cells (HUVECs)

Author: Available in link provided

Date of Publication : Available in link provided

Microenvironment responsive hypoxia-mimetic DFO composite hydrogel for on-demand neovascularization to promote tendon-to-bone healing COMPOSITES PART B-ENGINEERING Honghao Hou IF Rat,Human bone tissue Human umbilical vein endothelial cells (HUVECs)

Author: Available in link provided

Date of Publication : Available in link provided

Decreasing expression of HIF-1α, VEGF-A, and Ki67 with efficacy of neoadjuvant therapy in locally advanced cervical cancer. Tingkuan Zhao IHC Human 1:200 locally advanced cervical cancer (LACC) tissue,normal cervical tissue

Author: Available in link provided

Date of Publication : Available in link provided

3D hypoxia-mimicking and anti-synechia hydrogel enabling promoted neovascularization for renal injury repair and regeneration. Honghao Hou IF Rat,Human renal tissue Human umbilical vein endothelial cells (HUVECs)

Author: Available in link provided

Date of Publication : Available in link provided

Loss of NDUFS1 promotes gastric cancer progression by activating the mitochondrial ROS-HIF1α-FBLN5 signaling pathway. BRITISH JOURNAL OF CANCER Jin Zhou WB Human 1:1000 MKN45 cell,N87 cell

Author: Available in link provided

Date of Publication : Available in link provided

Biomimetic Hydrogel Containing Copper Sulfide Nanoparticles and Deferoxamine for Photothermal Therapy of Infected Diabetic Wounds Advanced Healthcare Materials Haijun Shen IHC Mouse 1:100 skin tissue

Author: Available in link provided

Date of Publication : Available in link provided

Ononin promotes radiosensitivity in lung cancer by inhibiting HIF-1α/VEGF pathway PHYTOMEDICINE Yi-Ming Zhang IF Human 1:200 NCI-H1299 cell,NCI-A549 cell

Author: Available in link provided

Date of Publication : Available in link provided

Peroxiredoxin 2 as a potential prognostic biomarker associated with angiogenesis in cervical squamous cell cancer Oncology Letters Ke Zhao IHC Human 1:100 cervical squamous cell cancer (CSCC) tissue

Author: Available in link provided

Date of Publication : Available in link provided

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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