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Primary Antibodies
SOCS-1 Antibody
SOCS-1 Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: R12-2360
Reactivity:Human,Mouse,Rat
Applications:IF/ICC,WB,IHC-p,ELISA
Modification:Unmodified/Total
Source:Polyclonal Rabbit
Storage and Stability:-20°C/1 year

$205
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SOCS-1 Antibody

Western blot analysis of lysate from Jurkat cells, using SOCS-1 antibody.

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Product Details
Product Name
SOCS-1 Antibody
Description
This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival. [provided by RefSeq, Jul 2008]
Catalog No
R12-2360
Reactivity
Human, Mouse, Rat
Applications
IF/ICC, WB, IHC-p, ELISA
Modification
Unmodified/Total
Source
Polyclonal Rabbit
Dilution
IF: 1:50-200 WB 1:500-2000, ELISA 1:10000-20000 IHC 1:50-300
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
-20°C/1 year
Other Name
SOCS1; SSI1; TIP3; Suppressor of cytokine signaling 1; SOCS-1; JAK-binding protein; JAB; STAT-induced STAT inhibitor 1; SSI-1; Tec-interacting protein 3; TIP-3
Molecular Weight (Da)
23551
Gene Name
SOCS1
Protein Name
Suppressor of cytokine signaling 1
Human Gene ID
8651
Human Swiss Prot No.
O15524
Immunogen
The antiserum was produced against synthesized peptide derived from human SOCS-1. AA range:49-98
Specificity
SOCS-1 Polyclonal Antibody detects endogenous levels of SOCS-1 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Publications (4)
Bu Shen Yi Sui Capsule Alleviates Neuroinflammation and Demyelination by Promoting Microglia toward M2 Polarization, Which Correlates with Changes in miR-124 and miR-155 in Experimental Autoimmune Encephalomyelitis

Author: Zha Zheng, Gao Yan-Fang, Ji Jing, Sun Ya-Qin, Li Jun-Ling, Qi Fang, Zhang Nan, Jin Liang-Yun, Xue Bing, Yang Tao, Fan Yong-Ping, Zhao Hui, Wang Lei

Date of Publication : 2021-03-16

Danzhi Jiangtang Capsule ameliorates kidney injury via inhibition of the JAK-STAT signaling pathway and increased antioxidant capacity in STZ-induced diabetic nephropathy rats

Author: Min Sun, Wenjie Bu, Yan Li, Jianliang Zhu, Jindong Zhao, Pingping Zhang, Lingling Gu, Wenna Zhang, Zhaohui Fang

Date of Publication : 2018-12-28

DJC Suppresses Advanced Glycation End Products-Induced JAK-STAT Signaling and ROS in Mesangial Cells

Author: Sun Min, Li Yan, Bu Wenjie, Zhao Jindong, Zhu Jianliang, Gu Lingling, Zhang Pingping, Fang Zhaohui

Date of Publication : 2017-05-29

Targeting androgen receptor with ASC-J9 attenuates cardiac injury and dysfunction in experimental autoimmune myocarditis by reducing M1-like macrophage

Author: Wenhan Ma, Ya Wang, Shuai Lu, LianHua Yan, Fen Hu, ZhaoHui Wang

Date of Publication : 2017-02-27

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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