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Primary Antibodies
PIK3CA H1047R (ABT454) Mouse mAb
PIK3CA H1047R (ABT454) Mouse mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: YM4909
Reactivity:Human
Applications:IHC,WB,IF,ELISA
Modification:Not Modified
Source:Mouse
Storage and Stability:Store at -20°C/1 year

$190
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PIK3CA H1047R (ABT454) Mouse mAb

Whole cell lysates were separated by 10% SDS-PAGE, and the membrane was blotted with anti-PIK3CA H1047R (ABT454) antibody. The HRP-conjugated Goat anti-Mouse IgG(H + L) antibody was used to detect the antibody. Lane 1: K562 Predicted band size: 124kDa Observed band size: 124kDa

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Product Details
Product Name
PIK3CA H1047R (ABT454) Mouse mAb
Description
The PIK3CA gene is located at 3Q26.3 and encodes a 124 kDa protein. The protein is composed of 85 kDa regulatory subunit and 110 kDa catalytic subunit. The most common mutations of PIK3CA occur in exon 9 and exon 20. H1047R, one of the most common mutations occurs in exon 20. PIK3CA plays an important role in the PI3K/AKT/mTOR signaling pathway, which can be activated by this mutation, closely related to the occurrence of tumors and disease progression. In non-small cell lung cancer, H1047R mutantion can phosphorylate Akt and activate downstream pathways to promote the survival and expansion of tumor cells.
Catalog No
YM4909
Reactivity
Human
Source
Mouse
Modification
Not Modified
Applications
IHC, WB, IF, ELISA
Dilution
IHC 1:100-500, WB 1:500-2000, IF 1:100-500, ELISA, 1:1000-5000
Purification
Protein G
Storage and Stability
P42336
Human Swiss Prot No.
PIP
Gene Name
GCDFP-15
Protein Name
5304
Gene ID
BRST-2,BRST2,GCDFP-15,GCDGP15,gp17,GPIP4,Gross cystic disease fluid protein 15,PIP,PIP_HUMAN,Prolactin induced protein,Prolactin inducible protein precursor,Prolactin-induced protein,Prolactin-inducible protein,SABP,Secretory actin binding protein,Secretory actin-binding protein
Other Name
The antibody can specifically recognize the h1047r mutation of human PIK3CA protein, and does not react with wild-type PIK3CA protein.
Specificity
The antibody is provided in liquid form in phosphate-buffered saline with 50% glycerol, 0.05% BSA, and 0.05% Proclin 300.
Formulation
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Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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