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Primary Antibodies
pVHL (ABT-PVHL) PathoELITE™ Mouse mAb
pVHL (ABT-PVHL) PathoELITE™ Mouse mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: YM6215R
Reactivity:Human
Applications:IHC
Modification:Not Modified
Source:Mouse
Storage and Stability:Store at -20°C/1 year

$70
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IHC Specialized Products
Pathology Grade Abs
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pVHL (ABT-PVHL) PathoELITE™ Mouse mAb

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Product Details
Product Name
pVHL (ABT-PVHL) PathoELITE™ Mouse mAb
Description
pVHL (Von Hippel-Lindau protein), with a molecular weight of approximately 30 kDa, is a tumor suppressor protein encoded by the VHL gene. Its primary function is to regulate intracellular protein degradation, particularly in relation to the hypoxia-inducible factor (HIF). pVHL is a crucial tumor suppressor that influences angiogenesis, metabolism, and tumor growth by modulating HIF degradation. Mutations in the VHL gene are the main driving factor of clear cell renal cell carcinoma (ccRCC) and are closely associated with hereditary diseases such as Von Hippel-Lindau disease. Pathological detection of pVHL and related targeted therapies play a significant role in cancer diagnosis and treatment.
Catalog No
YM6215R
Reactivity
Human
Source
Mouse
Modification
Not Modified
Applications
IHC
Dilution
Ready to Use for Immunohistochemistry
Storage and Stability
Store at -20°C/1 year
Human Swiss Prot No.
P40337
Gene Name
VHL
Protein Name
pVHL
Gene ID
7428
Other Name
von Hippel-Lindau disease tumor suppressor,Protein G7,pVHL
Specificity
The antibody can specifically recognize human pVHL protein.
Formulation
The antibody is provided in liquid form in phosphate-buffered saline with 50% glycerol, 0.05% BSA, and 0.05% Proclin 300.
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Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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