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E-Cadherin (ABT270) PathoELITE™ Mouse mAb
E-Cadherin (ABT270) PathoELITE™ Mouse mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: YM6127R
Reactivity:Human
Applications:IHC
Modification:Not Modified
Source:Mouse
Storage and Stability:Store at -20°C/1 year

$70
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IHC Specialized Products
Pathology Grade Abs
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E-Cadherin (ABT270) PathoELITE™ Mouse mAb

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Product Details
Product Name
E-Cadherin (ABT270) PathoELITE™ Mouse mAb
Description
E-Cadherein, 120kDa, is a critical regulator of epithelial junction formation. The E-cadherin internal domain binds with alpha, beta, gamma, and p120 catenins to anchor the ECAD complex to the actin cytoskeleton of the cell. E-cadherin is expressed in virtually all epithelial cells with the exception of adrenocortical cells. The expression in liver cells is weaker than in most other epithelia. ECAD is also expressed in melanocytes (adhering to squamous epithelial cells). Mesothelial cells and granulosa cells are ECAD negative. Mesenchymal cells and neural crest cells are mostly negative but some types may show a weak reaction. Testicular germinative cells are weakly positive. At present, it is commonly used to differentiate breast lobular cancer from ductal cancer (the former is often negative, the latter is often positive).
Catalog No
YM6127R
Reactivity
Human
Source
Mouse
Modification
Not Modified
Applications
IHC
Dilution
Ready to Use for Immunohistochemistry
Storage and Stability
Store at -20°C/1 year
Human Swiss Prot No.
P12830
Gene Name
CDH1
Protein Name
E-Cadherin
Gene ID
999
Other Name
Cadherin-1,CAM 120/80,Epithelial cadherin (E-cadherin),Uvomorulin,CD324,CDH1,CDHE
Specificity
The antibody can specifically recognize E-cadherin protein.
Formulation
The antibody is provided in liquid form in phosphate-buffered saline with 50% glycerol, 0.05% BSA, and 0.05% Proclin 300.
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Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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