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Primary Antibodies
ROCK1 (PT0305R) Rabbit mAb
ROCK1 (PT0305R) Rabbit mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: YM8179
Reactivity:Human,Mouse,Rat
Applications:WB,IHC,IF,IP,ELISA
Modification:Unmodified/ Total
Source:Rabbit Monoclonal
Storage and Stability:Store at -20°C/1 year

$190
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Recombinant Antibody
Sample Sized mAbs (Code: 5477)
Buy 1 Get 1 (Code: B1G1)
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ROCK1 (PT0305R) Rabbit mAb

Various whole cell lysates were separated by 4-8% SDS-PAGE, and the membrane was blotted with anti-ROCK1 (PT0305R) antibody. The HRP-conjugated Goat anti-Rabbit IgG(H + L) antibody was used to detect the antibody. Lane 1: C6 Predicted band size: 158kDa Observed band size: 158kDa

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Product Details
Product Name
ROCK1 (PT0305R) Rabbit mAb
Description
This gene encodes a protein serine/threonine kinase that is activated when bound to the GTP-bound form of Rho. The small GTPase Rho regulates formation of focal adhesions and stress fibers of fibroblasts, as well as adhesion and aggregation of platelets and lymphocytes by shuttling between the inactive GDP-bound form and the active GTP-bound form. Rho is also essential in cytokinesis and plays a role in transcriptional activation by serum response factor. This protein, a downstream effector of Rho, phosphorylates and activates LIM kinase, which in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity. A pseudogene, related to this gene, is also located on chromosome 18. [provided by RefSeq, Aug 2015],
Catalog No
YM8179
Reactivity
Human, Mouse, Rat
Source
Monoclonal Rabbit IgG, Kappa
Modification
Unmodified/ Total
Applications
WB,IHC,IF,IP,ELISA
Dilution
WB 1:1000-1:5000 IF 1:200-1:1000 ELISA 1:5000-1:20000 IP 1:50-1:200
Purification
Protein A
Storage and Stability
Store at -20°C/1 year
Human Swiss Prot No.
Q13464
Gene Name
Protein Name
ROCK1
Gene ID
6093
Other Name
ROCK1;Rho-associated protein kinase 1;Renal carcinoma antigen NY-REN-35;Rho-associated; coiled-coil-containing protein kinase 1;Rho-associated, coiled-coil-containing protein kinase I;ROCK-I;p160 ROCK-1;p160ROCK
Specificity
Endogenous
Formulation
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
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Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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