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Primary Antibodies
Bcl-XL (PT0244R) Rabbit mAb
Bcl-XL (PT0244R) Rabbit mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: YM8153
Reactivity:Human,Mouse,Rat
Applications:WB,IHC,IF,IP,ELISA
Modification:Unmodified/ Total
Source:Rabbit Monoclonal
Storage and Stability:Store at -20°C/1 year

$190
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Recombinant Antibody
Sample Sized mAbs (Code: 5477)
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Bcl-XL (PT0244R) Rabbit mAb

Various whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-Bcl-XL (PT0244R) antibody. The HRP-conjugated Goat anti-Rabbit IgG(H + L) antibody was used to detect the antibody. Lane 1:3T3-L1 Lane 2: C6 Lane 3: HeLa Lane 4: K562 Predicted band size: 26kDa Observed band size: 30kDa

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Product Details
Product Name
Bcl-XL (PT0244R) Rabbit mAb
Description
The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Alternative splicing results in multiple transcript variants encoding two different isoforms. The longer isoform acts as an apoptotic inhibitor and the shorter isoform acts as an apoptotic activator. [provided by RefSeq, Dec 2015],
Catalog No
YM8153
Reactivity
Human, Mouse, Rat
Source
Monoclonal Rabbit IgG, Kappa
Modification
Unmodified/ Total
Applications
WB,IHC,IF,IP,ELISA
Dilution
WB 1:1000-1:5000 IF 1:200-1:1000 ELISA 1:5000-1:20000 IP 1:50-1:200
Purification
Protein A
Storage and Stability
Store at -20°C/1 year
Human Swiss Prot No.
Q07817
Gene Name
BCL2L1
Protein Name
Bcl-2-like protein 1
Gene ID
598
Other Name
BCL2L1;BCL2L;BCLX;Bcl-2-like protein 1;Bcl2-L-1;Apoptosis regulator Bcl-X
Specificity
Endogenous
Formulation
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
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Publications (4)
The role of insulin-like growth factor 1 in ALS cell and mouse models: A mitochondrial protector. BRAIN RESEARCH BULLETIN Brain Res Bull. 2019 Jan;144:1 WB Mouse 1:400 spinal cord

Author: Available in link provided

Date of Publication : Available in link provided

Cancer Stem Cells are Regulated by STAT3 Signalling in Wilms Tumour. Journal of Cancer J Cancer. 2018; 9(8): 1486–1499 WB Human,Mouse 1:1000 G401-Xenografts G401 cell

Author: Available in link provided

Date of Publication : Available in link provided

The Antitumor Effect of Suicide Gene Therapy Using Bifidobacterium infantis–mediated Herpes Simplex Virus Thymidine Kinase/Ganciclovir in a Nude Mice Model of Renal Cell Carcinoma. UROLOGY 2014 Aug 12 WB Mouse 786-O cell-Xenograft

Author: Available in link provided

Date of Publication : Available in link provided

Tang, Qiusha, et al. "Combination of PEI-Mn0. 5Zn0. 5Fe2O4 nanoparticles and pHsp 70-HSV-TK/GCV with magnet-induced heating for treatment of hepatoma." International journal of nanomedicine 10 (2015): 7129.

Author: Available in link provided

Date of Publication : Available in link provided

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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