Fas (PT0128R) Rabbit mAb

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Catalog No: YM8071

Reactivity:Human

Applications:WB,IHC,IF,IP,ELISA

Modification:Unmodified/ Total

Source:Rabbit Monoclonal

Storage and Stability:Store at -20°C/1 year

Size:

Price/Quantity $190

Quantity:

Datasheet

SDS

Recombinant Antibody

Sample Sized mAbs (Code: 5477)

Buy 1 Get 1 (Code: B1G1)

Fas (PT0128R) Rabbit mAb

Various whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-Fas (PT0128R) antibody. The HRP-conjugated Goat anti-Rabbit IgG(H + L) antibody was used to detect the antibody. Lane 1: HeLa Predicted band size: 38kDa Observed band size: 40kDa

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Antibodies 1-2 business day, ELISA kits 2-3 business day lead time

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Product Details

Product Name

Fas (PT0128R) Rabbit mAb

Description

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains a death domain. It has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system. The interaction of this receptor with its ligand allows the formation of a death-inducing signaling complex that includes Fas-associated death domain protein (FADD), caspase 8, and caspase 10. The autoproteolytic processing of the caspases in the complex triggers a downstream caspase cascade, and leads to apoptosis. This receptor has been also shown to activate NF-kappaB, MAPK3/ERK1, and MAPK8/JNK, and is found to be involved in transducing the proliferating signals in normal diploid fibroblast and T cells. Several alternatively spliced transcript variants have been described, s

Catalog No

YM8071

Reactivity

Human

Source

Monoclonal Rabbit IgG, Kappa

Modification

Unmodified/ Total

Applications

WB,IHC,IF,IP,ELISA

Dilution

WB 1:1000-1:5000 IF 1:200-1:1000 ELISA 1:5000-1:20000 IP 1:50-1:200

Purification

Protein A

Storage and Stability

Store at -20°C/1 year

Human Swiss Prot No.

P25445

Gene Name

FAS

Protein Name

Tumor necrosis factor receptor superfamily member 6

Gene ID

355

Other Name

FAS;APT1;FAS1;TNFRSF6;Tumor necrosis factor receptor superfamily member 6;Apo-1 antigen;Apoptosis-mediating surface antigen FAS;FASLG receptor;CD antigen CD95

Specificity

Endogenous

Formulation

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA