Smad2 (PT0111R) Rabbit mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: YM8064

Reactivity:Human,Mouse,Rat

Applications:WB,IF,IP,ELISA

Modification:Unmodified/ Total

Source:Rabbit Monoclonal

Storage and Stability:Store at -20°C/1 year

Size:

Price/Quantity $190

Quantity:

Datasheet

SDS

Recombinant Antibody

Sample Sized mAbs (Code: 5477)

Buy 1 Get 1 (Code: B1G1)

Smad2 (PT0111R) Rabbit mAb

Various whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-Smad2 (PT0111R) antibody. The HRP-conjugated Goat anti-Rabbit IgG(H + L) antibody was used to detect the antibody. Lane 1:A549 treated with TPA of 48 hours Lane 2: Hela Lane 3: RAW264.7 Lane 4: C6 Predicted band size: 58kDa Observed band size: 58kDa

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Antibodies 1-2 business day, ELISA kits 2-3 business day lead time

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Product Details

Product Name

Smad2 (PT0111R) Rabbit mAb

Description

The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signal of the transforming growth factor (TGF)-beta, and thus regulates multiple cellular processes, such as cell proliferation, apoptosis, and differentiation. This protein is recruited to the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation (SARA) protein. In response to TGF-beta signal, this protein is phosphorylated by the TGF-beta receptors. The phosphorylation induces the dissociation of this protein with SARA and the association with the family member SMAD4. The association with SMAD4 is important for the translocation

Catalog No

YM8064

Reactivity

Human, Mouse, Rat

Source

Monoclonal Rabbit IgG, Kappa

Modification

Unmodified/ Total

Applications

WB,IF,IP,ELISA

Dilution

WB 1:1000-1:5000 IF 1:200-1:1000 ELISA 1:5000-1:20000 IP 1:50-1:200

Purification

Protein A

Storage and Stability

Store at -20°C/1 year

Human Swiss Prot No.

Q15796

Gene Name

SMAD2

Protein Name

Mothers against decapentaplegic homolog 2

Gene ID

4087

Other Name

SMAD2;MADH2;MADR2;Mothers against decapentaplegic homolog 2;MAD homolog 2;Mothers against DPP homolog 2;JV18-1;Mad-related protein 2;hMAD-2;SMAD family member 2;SMAD 2;Smad2;hSMAD2

Specificity

Endogenous

Formulation

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

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Publications (5)