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Primary Antibodies
Caspase-9 (PT0299R) Rabbit mAb
Caspase-9 (PT0299R) Rabbit mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: YM8173
Reactivity:Human,Mouse,Rat
Applications:WB,IHC,IF,IP,ELISA
Modification:Unmodified/ Total
Source:Rabbit Monoclonal
Storage and Stability:Store at -20°C/1 year

$190
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Recombinant Antibody
Sample Sized mAbs (Code: 5477)
Buy 1 Get 1 (Code: B1G1)
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Caspase-9 (PT0299R) Rabbit mAb

Various whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-Caspase-9 (PT0299R) antibody. The HRP-conjugated Goat anti-Rabbit IgG(H + L) antibody was used to detect the antibody. Lane 1: Hela Lane 2: THP-1 Predicted band size: 46kDa Observed band size: 40kDa

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Product Details
Product Name
Caspase-9 (PT0299R) Rabbit mAb
Description
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1; this step is thought to be one of the earliest in the caspase activation cascade. This protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013],
Catalog No
YM8173
Reactivity
Human, Mouse, Rat
Source
Monoclonal Rabbit IgG, Kappa
Modification
Unmodified/ Total
Applications
WB,IHC,IF,IP,ELISA
Dilution
WB 1:1000-1:5000 IF 1:200-1:1000 ELISA 1:5000-1:20000 IP 1:50-1:200
Purification
Protein A
Storage and Stability
Store at -20°C/1 year
Human Swiss Prot No.
P55211
Gene Name
CASP9
Protein Name
Caspase9
Gene ID
842
Other Name
CASP9;MCH6;Caspase-9;CASP-9;Apoptotic protease Mch-6;Apoptotic protease-activating factor 3;APAF-3;ICE-like apoptotic protease 6;ICE-LAP6
Specificity
Endogenous
Formulation
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
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Publications (24)
Decreased thioredoxin reductase 3 expression promotes nickel-induced damage to cardiac tissue via activating oxidative stress-induced apoptosis and inflammation

Author: Available in link provided

Date of Publication : Available in link provided

Synthesis of macromolecular Astragalus polysaccharide-nano selenium complex and the inhibitory effects on HepG2 cells WB Human /HepG2 cell

Author: Available in link provided

Date of Publication : Available in link provided

The inhibitory effects of selenium nanoparticles modified by fructose-enriched polysaccharide from Codonopsis pilosula on HepG2 cells. INDUSTRIAL CROPS AND PRODUCTS Ind Crop Prod. 2022 Feb;176:114335 WB Human HepG2 cell

Author: Available in link provided

Date of Publication : Available in link provided

Microcystin-LR Induced Apoptosis in Rat Sertoli Cells via the Mitochondrial Caspase-Dependent Pathway: Role of Reactive Oxygen Species. Frontiers in Physiology 2016 Sep 09 WB Rat Sertoli cell

Author: Available in link provided

Date of Publication : Available in link provided

Atrazine Causes Autophagy- and Apoptosis-Related Neurodegenerative Effects in Dopaminergic Neurons in the Rat Nigrostriatal Dopaminergic System. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2015 Jun 12 WB Rat ventral midbrain

Author: Available in link provided

Date of Publication : Available in link provided

Effect of annexin A7 suppression on the apoptosis of gastric cancer cells. MOLECULAR AND CELLULAR BIOCHEMISTRY Mol Cell Biochem. 2017 May;429(1):33-43 WB Human,Mouse BGC823 cell-xenograft BGC823 cell

Author: Available in link provided

Date of Publication : Available in link provided

Forkhead Box Protein M1 Promotes Nasopharyngeal Carcinoma Cell Tumorigenesis Possibly via the Wnt/β-Catenin Signaling Pathway. MEDICAL SCIENCE MONITOR Med Sci Monitor. 2021; 27: e931970-1–e931970-10 WB Mouse CNE-1s，CNE-2s

Author: Available in link provided

Date of Publication : Available in link provided

The role of Se content in improving anti-tumor activities and its potential mechanism for selenized Artemisia sphaerocephala polysaccharides. Food & Function Food Funct. 2021 Mar;12(5):2058-2074 WB Human HepG2 cell

Author: Available in link provided

Date of Publication : Available in link provided

SPAG6 silencing inhibits the growth of the malignant myeloid cell lines SKM-1 and K562 via activating p53 and caspase activation-dependent apoptosis. INTERNATIONAL JOURNAL OF ONCOLOGY 2015 Feb 01 WB Human SKM-1 cell， K562 cell

Author: Available in link provided

Date of Publication : Available in link provided

Mitochondrial pathway and endoplasmic reticulum stress participate in the photosensitizing effectiveness of AE‐PDT in MG63 cells. Cancer Medicine 2016 Oct 03 WB Human MG63 cell

Author: Available in link provided

Date of Publication : Available in link provided

LC3-II may mediate ATR-induced mitophagy in dopaminergic neurons through SQSTM1/p62 pathway. ACTA BIOCHIMICA ET BIOPHYSICA SINICA 2018 Oct 01 WB Rat 1:1000 substantia nigra (SNpc) PC-12 cell

Author: Available in link provided

Date of Publication : Available in link provided

Ad-p53 enhances the sensitivity of triple-negative breast cancer MDA-MB-468 cells to the EGFR inhibitor gefitinib. ONCOLOGY REPORTS 2014 Dec 11 WB Human MDA-MB-468 cell

Author: Available in link provided

Date of Publication : Available in link provided

VX-680 induces p53-mediated apoptosis in human cholangiocarcinoma cells. ANTI-CANCER DRUGS Anti-Cancer Drug. 2018 Nov;29(10):1004-1010 WB Human 1 : 1000 HCCC-9810 cell

Author: Available in link provided

Date of Publication : Available in link provided

5,6-Dihydroxy-3,7,4′-trimethoxyflavonol induces G2/M cell cycle arrest and apoptosis in human hepatocellular carcinoma cells. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH J Asian Nat Prod Res. 2016;18(11):1079-1090 WB Human 1:1000 HepG-2 cell

Author: Available in link provided

Date of Publication : Available in link provided

Apoptosis triggered by pyropheophorbide-α methyl ester-mediated photodynamic therapy in a giant cell tumor in bone. LASER PHYSICS Laser Phys. 2014 May;24(6):066002 WB Human SGC-0404 cell

Author: Available in link provided

Date of Publication : Available in link provided

Fucoidan inhibits proliferation of the SKM-1 acute myeloid leukaemia cell line via the activation of apoptotic pathways and production of reactive oxygen species. Molecular Medicine Reports Mol Med Rep. 2015 Nov;12(5):6649-6655 WB Human SKM-1 cell

Author: Available in link provided

Date of Publication : Available in link provided

Mitochondrial separation protein inhibitor inhibits cell apoptosis in rat lungs during intermittent hypoxia. Experimental and Therapeutic Medicine 2019 Mar 01 WB Human,Rat 1:1000 lung WRTL1 cell

Author: Available in link provided

Date of Publication : Available in link provided

5, 6-Dihydroxy-3, 7, 4′-trimethoxyflavonol induces G2/M cell cycle arrest and apoptosis in human hepatocellular carcinoma cells." Journal of Asian natural products research 18.11 (2016): 1079-1090.

Author: Available in link provided

Date of Publication : Available in link provided

Mitochondrial pathway and endoplasmic reticulum stress participate in the photosensitizing effectiveness of AE‐PDT in MG63 cells. Cancer Medicine 2016 Oct 03 WB Human MG63 cell

Author: Available in link provided

Date of Publication : Available in link provided

Flavonoid-Rich Extract of Oldenlandia diffusa (Willd.) Roxb. Inhibits Gastric Cancer by Activation of Caspase-Dependent Mitochondrial Apoptosis Chinese Journal of Integrative Medicine Qiu-lan Wang WB Human

Author: Available in link provided

Date of Publication : Available in link provided

Flavonoid-Rich Extract of Oldenlandia diffusa (Willd.) Roxb. Inhibits Gastric Cancer by Activation of Caspase-Dependent Mitochondrial Apoptosis Chinese Journal of Integrative Medicine Qiu-lan Wang WB Human

Author: Available in link provided

Date of Publication : Available in link provided

Role of Txnrd3 in NiCl2-induced kidney cell apoptosis in mice: Potential therapeutic effect of melatonin. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY Ziwei Zhang WB Mouse 1:2000 kidney

Author: Available in link provided

Date of Publication : Available in link provided

The outer membrane protein Tp92 of Treponema pallidum delays human neutrophil apoptosis via the ERK, PI3K/Akt, and NF-κB pathways. MOLECULAR MICROBIOLOGY Yimou Wu WB Human human polymorphonuclear neutrophils (hPMNs)

Author: Available in link provided

Date of Publication : Available in link provided

Protective effect of cornuside on OGD/R injury in SH-SY5Y cells and its underlying mechanism. BRAIN RESEARCH Jianwei Gong WB Human SH-SY5Y cell

Author: Available in link provided

Date of Publication : Available in link provided

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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