Mucin 5AC (PT0248R) Rabbit mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: YM8156

Reactivity:Human,Mouse,Rat

Applications:WB,IHC,IF,IP,ELISA

Modification:Unmodified/ Total

Source:Rabbit Monoclonal

Storage and Stability:Store at -20°C/1 year

Size:

Price/Quantity $190

Quantity:

Datasheet

SDS

Recombinant Antibody

Sample Sized mAbs (Code: 5477)

Buy 1 Get 1 (Code: B1G1)

Mucin 5AC (PT0248R) Rabbit mAb

Whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-Mucin 5AC (PT0248R) antibody. The HRP-conjugated Goat anti-Rabbit IgG(H + L) antibody was used to detect the antibody. Lane 1: HT-29 Predicted band size: 527kDa Observed band size: 130-600kDa

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Antibodies 1-2 business day, ELISA kits 2-3 business day lead time

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Product Details

Product Name

Mucin 5AC (PT0248R) Rabbit mAb

Description

domain:The cysteine residues in the Cys-rich subdomain repeats are not involved in disulfide bonding.,function:Gel-forming glycoprotein of gastric and respiratoy tract epithelia that protects the mucosa from infection and chemical damage by binding to inhaled microrganisms and particules that are subsequently removed by the mucocilary system.,PTM:C-, O- and N-glycosylated. O-glycosylated on the Thr-/Ser-rich tandem repeats. C-mannosylation in the Cys-rich subdomains may be required for proper folding of these regions and for export from the endoplasmic reticulum during biosynthesis.,PTM:Proteolytic cleavage in the C-terminal is initiated early in the secretory pathway and does not involve a serine protease. The extent of cleavage is increased in the acidic parts of the secretory pathway. Cleavage generates a reactive group which could link the protein to a primary amide.,similarity:Contains 1 CTCK (C-terminal cystine knot-like) domain.,similarity:Contains 2 VWFC domains.,similarity:Contains 4 VWFD domains.,subunit:Multimeric. Interacts with H.pylori in the gastric epithelium, Barrett's esophagus as well as in gastric metaplasia of the duodenum (GMD).,tissue specificity:Highly expressed in surface mucosal cells of respiratory tract and stomach epithelia. Overexpressed in a number of carcinomas. Also expressed in Barrett's esophagus epithelium and in the proximal duodenum.,

Catalog No

YM8156

Reactivity

Human, Mouse, Rat

Source

Monoclonal Rabbit IgG, Kappa

Modification

Unmodified/ Total

Applications

WB,IHC,IF,IP,ELISA

Dilution

WB 1:1000-1:5000 IF 1:200-1:1000 ELISA 1:5000-1:20000 IP 1:50-1:200

Purification

Protein A

Storage and Stability

Store at -20°C/1 year

Human Swiss Prot No.

P98088

Gene Name

MUC5AC MUC5

Protein Name

Mucin-5AC (MUC-5AC) (Gastric mucin) (Lewis B blood group antigen) (LeB) (Major airway glycoprotein) (Mucin-5 subtype AC, tracheobronchial) (Tracheobronchial mucin) (TBM) (Fragments)

Gene ID

Other Name

Mucin-5AC;Gastric mucin;Major airway glycoprotein;Mucin-5 subtype AC, tracheobronchial;Tracheobronchial mucin;MUC5;MUC5AC

Specificity

Endogenous

Formulation

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA