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Primary Antibodies
FAK (PT0245R) Rabbit mAb
FAK (PT0245R) Rabbit mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: YM8154
Reactivity:Human,Mouse,Rat
Applications:WB,IHC,IF,IP,ELISA
Modification:Unmodified/ Total
Source:Rabbit Monoclonal
Storage and Stability:Store at -20°C/1 year

$190
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Recombinant Antibody
Sample Sized mAbs (Code: 5477)
Buy 1 Get 1 (Code: B1G1)
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FAK (PT0245R) Rabbit mAb

Various whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-FAK (PT0245R) antibody. The HRP-conjugated Goat anti-Rabbit IgG(H + L) antibody was used to detect the antibody. Lane 1: Mosue brain Lane 2: Rat brain Lane 3: MCF7 Lane 4: HCT-116 Predicted band size: 119kDa Observed band size: 119kDa

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Product Details
Product Name
FAK (PT0245R) Rabbit mAb
Description
protein tyrosine kinase 2(PTK2) Homo sapiens    This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene, but the full-length natures of only four of them have been determined. [provided by RefSeq, Oct 2015],
Catalog No
YM8154
Reactivity
Human, Mouse, Rat
Source
Monoclonal Rabbit IgG, Kappa
Modification
Unmodified/ Total
Applications
WB,IHC,IF,IP,ELISA
Dilution
WB 1:1000-1:5000 IF 1:200-1:1000 ELISA 1:5000-1:20000 IP 1:50-1:200
Purification
Protein A
Storage and Stability
Store at -20°C/1 year
Human Swiss Prot No.
Q05397
Gene Name
PTK2
Protein Name
Focal adhesion kinase 1
Gene ID
5747
Other Name
PTK2;FAK;FAK1;Focal adhesion kinase 1;FADK 1;Focal adhesion kinase-related nonkinase;FRNK;Protein phosphatase 1 regulatory subunit 71;PPP1R71;Protein-tyrosine kinase 2;p125FAK;pp125FAK
Specificity
Endogenous
Formulation
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
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Publications (6)
Albumin Fusion at the N-Terminus or C-Terminus of HM-3 Leads to Improved Pharmacokinetics and Bioactivities. Biomedicines Biomedicines. 2021 Sep;9(9):1084 WB Mouse Murine melanoma cells (B16F10)

Author: Available in link provided

Date of Publication : Available in link provided

HM-3-HSA exhibits potent anti-angiogenesis and antitumor activity in hepatocellular carcinoma. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES Eur J Pharm Sci. 2021 Sep;:106017 WB Human HUVECs

Author: Available in link provided

Date of Publication : Available in link provided

Dissecting the roles of Ephrin-A3 in malignant peripheral nerve sheath tumor by TALENs. ONCOLOGY REPORTS Oncol Rep. 2015 Jul;34(1):391-398 WB Human ST88-14 cell, sNF96.2 cell

Author: Available in link provided

Date of Publication : Available in link provided

Exosomes derived from 5-fluorouracil-resistant colon cancer cells are enriched in GDF15 and can promote angiogenesis. Journal of Cancer J Cancer. 2020; 11(24): 7116–7126 WB Human 1 : 1000 HCT-15/FU exosome

Author: Available in link provided

Date of Publication : Available in link provided

Lu, Jian, et al. "Role of LKB1 in migration and invasion of Cr (VI)-transformed human bronchial epithelial Beas-2B cells." Anti-cancer drugs 29.7 (2018): 660-673.

Author: Available in link provided

Date of Publication : Available in link provided

Integrin β4 Regulates Cell Migration of Lung Adenocarcinoma Through FAK Signaling MOLECULAR BIOTECHNOLOGY Zhang Shusen WB Human 1:1000 PC9 cell,NCIH1975 cell,A549 cell

Author: Available in link provided

Date of Publication : Available in link provided

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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