PTEN (PT0226R) Rabbit mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: YM8142

Reactivity:Human,Mouse,Rat

Applications:WB,IF,IP,ELISA

Modification:Unmodified/ Total

Source:Rabbit Monoclonal

Storage and Stability:Store at -20°C/1 year

Size:

Price/Quantity $190

Quantity:

Datasheet

SDS

Recombinant Antibody

Sample Sized mAbs (Code: 5477)

Buy 1 Get 1 (Code: B1G1)

PTEN (PT0226R) Rabbit mAb

Various whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-PTEN (PT0226R) antibody. The HRP-conjugated Goat anti-Rabbit IgG(H + L) antibody was used to detect the antibody. Lane 1: MCF7 Lane 2: Mouse testis Lane 3: Rat testis Lane 4: Hela Predicted band size: 47kDa Observed band size: 56kDa

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Antibodies 1-2 business day, ELISA kits 2-3 business day lead time

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Product Details

Product Name

PTEN (PT0226R) Rabbit mAb

Description

phosphatase and tensin homolog(PTEN) Homo sapiens This gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded by this gene is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates. It negatively regulates intracellular levels of phosphatidylinositol-3,4,5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT/PKB signaling pathway. The use of a non-canonical (CUG) upstream initiation site produces a longer isoform that initiates translation with a leucine, and is thought to be preferentially associated with the mitochondrial inner membrane. This longer isoform may help regulate ener

Catalog No

YM8142

Reactivity

Human, Mouse, Rat

Source

Monoclonal Rabbit IgG, Kappa

Modification

Unmodified/ Total

Applications

WB,IF,IP,ELISA

Dilution

WB 1:1000-1:5000 IF 1:200-1:1000 ELISA 1:5000-1:20000 IP 1:50-1:200

Purification

Protein A

Storage and Stability

Store at -20°C/1 year

Human Swiss Prot No.

P60484

Gene Name

PTEN MMAC1 TEP1

Protein Name

Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (EC 3.1.3.16) (EC 3.1.3.48) (EC 3.1.3.67) (Mutated in multiple advanced cancers 1) (Phosphatase and

Gene ID

5728

Other Name

Specificity

Endogenous

Formulation

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA