NLRP3 (PT0049R) Rabbit mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: YM8024

Reactivity:Human,Mouse,Rat

Applications:WB,IHC,IF,IP,ELISA

Modification:Unmodified/ Total

Source:Rabbit Monoclonal

Storage and Stability:Store at -20°C/1 year

Size:

Price/Quantity $190

Quantity:

Datasheet

SDS

Recombinant Antibody

Sample Sized mAbs (Code: 5477)

Buy 1 Get 1 (Code: B1G1)

NLRP3 (PT0049R) Rabbit mAb

Various whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-NLRP3 (PT0049R) antibody. The HRP-conjugated Goat anti-Rabbit IgG(H + L) antibody was used to detect the antibody. Lane 1: J774A.1 Lane 2: RAW364.7 Lane 3: THP-1 Predicted band size: 118kDa Observed band size: 118kDa

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Antibodies 1-2 business day, ELISA kits 2-3 business day lead time

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Product Details

Product Name

NLRP3 (PT0049R) Rabbit mAb

Description

This gene encodes a pyrin-like protein containing a pyrin domain, a nucleotide-binding site (NBS) domain, and a leucine-rich repeat (LRR) motif. This protein interacts with the apoptosis-associated speck-like protein PYCARD/ASC, which contains a caspase recruitment domain, and is a member of the NALP3 inflammasome complex. This complex functions as an upstream activator of NF-kappaB signaling, and it plays a role in the regulation of inflammation, the immune response, and apoptosis. Mutations in this gene are associated with familial cold autoinflammatory syndrome (FCAS), Muckle-Wells syndrome (MWS), chronic infantile neurological cutaneous and articular (CINCA) syndrome, and neonatal-onset multisystem inflammatory disease (NOMID). Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Alternative 5' UTR structures are s

Catalog No

YM8024

Reactivity

Human, Mouse, Rat

Source

Monoclonal Rabbit IgG, Kappa

Modification

Unmodified/ Total

Applications

WB,IHC,IF,IP,ELISA

Dilution

WB 1:500-1:5000 IF 1:200-1:1000 ELISA 1:5000-1:20000 IP 1:50-1:200

Purification

Protein A

Storage and Stability

Store at -20°C/1 year

Human Swiss Prot No.

Q96P20

Gene Name

NLRP3

Protein Name

NACHT LRR and PYD domains-containing protein 3

Gene ID

114548

Other Name

NLRP3;C1orf7;CIAS1;NALP3;PYPAF1;NACHT, LRR and PYD domains-containing protein 3;Angiotensin/vasopressin receptor AII/AVP-like;Caterpiller protein 1.1CLR1.1;Cold autoinflammatory syndrome 1 protein;Cryopyrin;PYRIN-containing APAF1-like protein 1

Specificity

Endogenous

Formulation

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

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Publications (22)