CD117 (C-kit) (AB1377) mouse mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: V0486

Species Reactivity:Human;

Application:Immunohistochemistry (IHC)

Host:Mouse

Clonality:Monoclonal

Storage and Stability:Store at-20℃. Avoid freeze / thaw cycles.

Size:

Price/Quantity $75

Quantity:

Datasheet

SDS

Pathological Grade Antibodies

25% OFF (Code: 25SS)

CD117 (C-kit) (AB1377) mouse mAb

Delivery

Freight Charges

Utilize our shipping calculator at checkout to view

Lead Time

Antibodies 1-2 business day, ELISA kits 2-3 business day lead time

Telephone

408-747-0185

Fax

408-747-0145

order@assaybiotech.com

Promotions

Product Details

Product Name

CD117 (C-kit) (AB1377) mouse mAb

Description

CD117 is a cell membrane protein encoded by the c-kit proto-oncogene and is a type III transmembrane protein tyrosine kinase growth factor receptor. CD117 is expressed in mast cells, melanocytes and interstitial cells of Cajal. CD117 is positive in 80-100% of gastric stromal sarcoma (GIST) . CD117, as a specific marker for immunohistochemical examination of gastric stromal sarcoma (GIST) , can be used to clinically guide the personalized target drug (Gleevec) treatment of GIST patients. CD117 can also be used to identify mast cell tumors in lymphoma and as a marker for some testicular germ cell tumors.

Catalog No

V0486

Species Reactivity

Human;

Clonality

Monoclonal

Host

Mouse

Modifcation

Unmodified

Clone

AB1377

Isotype

IgG2b, kappa

Application

Immunohistochemistry (IHC)

Application Dilutions

IHC, 1:50-1:200

Immunogen

A synthetic peptide corresponding to the amino acid region 300 - 400 of the human CD117 protein.

Specificity

The antibody can specifically recognize human CD117 protein.

Formulation

The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.05% Proclin 300.

Purification

The antibody was purified by affinity chromatography using a specific immunogen.

Storage and Stability

Store at-20℃. Avoid freeze / thaw cycles.

Gene Name

KIT

Gene ID

3815

Human swiss

P10721

Protein Name

CD117

Synonyms

C Kit, c-Kit, c-Kit Ligand, CD117, Kit, Kit Ligand, KIT oncogene, KIT proto oncogene receptor tyrosine kinase, KIT_HUMAN, Mast cell growth factor receptor, Mast/stem cell growth factor receptor Kit, MGF, p145 c-kit, PBT, Piebald trait protein, Proto oncogene c Kit, Proto oncogene tyrosine protein kinase Kit, Proto-oncogene c-Kit, SCF Receptor, SCFR, soluble KIT variant 1, Steel Factor Receptor, Stem cell factor receptor, tyrosine protein kinase Kit, Tyrosine-protein kinase Kit, v kit Hardy Zuckerman 4 feline sarcoma viral oncogene homolog, v kit Hardy Zuckerman 4 feline sarcoma viral oncogene like protein, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog