Anti-Human P53 (ABT002) Mouse Monoclonal Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: V0428

Reactivity:Human

Application:IHC,WB

Modification:Unmodified/ Total

Source:Monoclonal Mouse

Storage and Stability:Stable at -20°C for at least 1 year.

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Datasheet

SDS

Immunohistochemical

Sample Sized mAbs 5477

Pathology Grade Abs

Anti-Human P53 (ABT002) Mouse Monoclonal Antibody

Hela whole cell lysates were separated by 10% SDS-PAGE, and the membrane was blotted with anti-P53(ABT002)antibody. The HRP-conjugated Goat anti-Mouse IgG(H + L) antibody was used to detect the antibody. Lane 1: Hela Predicted band size: 53kDa Observed band size: 53kDa

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Antibodies 1-2 business day, ELISA kits 2-3 business day lead time

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Product Details

Product Name

Anti-Human P53 (ABT002) Mouse Monoclonal Antibody

Description

tumor protein p53(TP53) Homo sapiens This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277). [provided by RefSeq, Feb 2013],

Catalog No

V0428

Reactivity

Human

Application

IHC,WB

Modification

Unmodified/ Total

Source

Monoclonal Mouse

Storage and Stability

Stable at -20°C for at least 1 year.

Other Name

Antigen NY-CO-13, BCC7, Cellular tumor antigen p53, FLJ92943, LFS1, Mutant tumor protein 53, p53, p53 tumor suppressor, P53_HUMAN, Phosphoprotein p53, Tp53, Transformation related protein 53, TRP53, tumor antigen p55, Tumor protein 53, Tumor protein p53, Tumor suppressor p53

Gene Name

TP53

UniProtKB

P04637

Clone ID

ABT002

Isotype

IgG2a, Kappa

Localization

Nuclear

Positive Tissue Control

Colonadeno carcinoma/ Ovarian serous adenocarcinoma

Specificity

The antibody can recognize human wild type and mutant P53 protein. In western blotting of wild type HEK293 cell lysate, the antibody can label a 53 kDa band corresponding to P53, while there is no band detected in P53 knock out HEK293 cell lysate.

Formulation

PBS, pH7.2, 0.03% Proclin 300, 50% glycerol