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Anti-Human Claudin 18 (ABT158) Mouse Monoclonal Antibody
Anti-Human Claudin 18 (ABT158) Mouse Monoclonal Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: V0261
Reactivity:Human
Application:IHC
Modification:Unmodified/ Total
Source:Monoclonal Mouse
Storage and Stability:Stable at -20°C for at least 1 year.

$Sample Size
Product Details
Product Name
Anti-Human Claudin 18 (ABT158) Mouse Monoclonal Antibody
Description
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is upregulated in patients with ulcerative colitis and highly overexpressed in infiltrating ductal adenocarcinomas. PKC/MAPK/AP-1 (protein kinase C/mitogen-activated protein kinase/activator protein-1) dependent pathway regulates the expression of this gene in gastric cells. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jun 2010],
Catalog No
V0261
Reactivity
Human
Application
IHC
Modification
Unmodified/ Total
Source
Monoclonal Mouse
Storage and Stability
Stable at -20°C for at least 1 year.
Other Name
Claudin 18, Claudin-18, CLD18_HUMAN, CLDN18, SFTA5, SFTPJ
Gene Name
CLDN18
UniProtKB
P56856
Clone ID
ABT158
Isotype
IgG1, kappa
Localization
Membranous
Positive Tissue Control
Stomach
Specificity
The antibody can specifically recognize both human Claudin 18.1 and Claudin 18.2 protein.
Formulation
PBS, pH7.2, 0.03% Proclin 300, 50% glycerol
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