Anti-Human Myelin Basic Protein(MBP) (ABT-MBP) Mouse Monoclonal Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: V0099

Reactivity:Human

Application:IHC

Modification:Unmodified/ Total

Source:Monoclonal Mouse

Storage and Stability:Stable at -20°C for at least 1 year.

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Datasheet

SDS

Immunohistochemical

Sample Sized mAbs 5477

Pathology Grade Abs

Anti-Human Myelin Basic Protein(MBP) (ABT-MBP) Mouse Monoclonal Antibody

Human cerebrum tissue was stained with Anti-Myelin Basic Protein(MBP) (ABT-MBP) Antibody

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Antibodies 1-2 business day, ELISA kits 2-3 business day lead time

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Product Details

Product Name

Anti-Human Myelin Basic Protein(MBP) (ABT-MBP) Mouse Monoclonal Antibody

Description

The protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. However, MBP-related transcripts are also present in the bone marrow and the immune system. These mRNAs arise from the long MBP gene (otherwise called "Golli-MBP") that contains 3 additional exons located upstream of the classic MBP exons. Alternative splicing from the Golli and the MBP transcription start sites gives rise to 2 sets of MBP-related transcripts and gene products. The Golli mRNAs contain 3 exons unique to Golli-MBP, spliced in-frame to 1 or more MBP exons. They encode hybrid proteins that have N-terminal Golli aa sequence linked to MBP aa sequence. The second family of transcripts contain only MBP exons and produce the well characterized myelin basic proteins. This complex gene structure is conserved among species suggesting that

Catalog No

V0099

Reactivity

Human

Application

IHC

Modification

Unmodified/ Total

Source

Monoclonal Mouse

Storage and Stability

Stable at -20°C for at least 1 year.

Other Name

GDB, Golli MBP, Golli MBP; myelin basic protein, Hemopoietic MBP, HMBPR, HUGO, MBP, MBP_CAVPO, MBP_HUMAN, MGC99675, MLD, Myelin A1 protein, Myelin A1 Protein, basic, Myelin basic protein, Myelin Deficient, Myelin membrane encephalitogenic protein, OTTHUMP00000163776, OTTHUMP00000174387, OTTHUMP00000174388, SHI, Shiverer, SP

Gene Name

MBP

UniProtKB

P02686

Clone ID

ABT-MBP

Isotype

IgG1, Kappa

Localization

Cytoplasmic

Positive Tissue Control

Brain/ Hippocampus