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Primary Antibodies
PDH-E1α Monoclonal Antibody
PDH-E1α Monoclonal Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: N0725
Reactivity:Human,Mouse,Rat,Bovine,Dog,Pig
Applications:WB,IF/ICC
Modification:Unmodfied/ Total
Source:Monoclonal Mouse
Storage and Stability:-20°C/1 year

$210
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PDH-E1α Monoclonal Antibody

Western Blot analysis using PDH-E1α Monoclonal Antibody against A549. HeLa cell lysate.

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Telephone
408-747-0185
Fax
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Email
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Product Details
Product Name
PDH-E1α Monoclonal Antibody
Description
The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits.This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2010],
Catalog No
N0725
Reactivity
Human,Mouse,Rat,Bovine,Dog,Pig
Applications
WB,IF/ICC
Modification
Unmodfied/ Total
Source
Monoclonal Mouse
Dilution
Western Blot: 1/1000 - 1/2000. Immunofluorescence: 1/100 - 1/500. Not yet tested in other applications.
Purification
Affinity purification
Concentration
1 mg/ml
Storage and Stability
-20°C/1 year
Other Name
PDHA1; PHE1A; Pyruvate dehydrogenase E1 component subunit alpha; somatic form, mitochondrial; PDHE1-A type I
Molecular Weight (Da)
Gene Name
PDHA1
Protein Name
Pyruvate dehydrogenase E1 component subunit alpha somatic form mitochondrial
Human Gene ID
5160
Human Swiss Prot No.
P08559
Immunogen
Purified recombinant human PDH-E1α (C-terminus) protein fragments expressed in E.coli.
Specificity
PDH-E1α Monoclonal Antibody detects endogenous levels of PDH-E1α protein.
Formulation
Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol.
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Catalog No: N0725

PDH-E1α Monoclonal Antibody

Price/Quantity:
$210

Size:
50μL

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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