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Primary Antibodies
PCNA Monoclonal Antibody(12D10)
PCNA Monoclonal Antibody(12D10)

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: N1295
Reactivity:Human,Rat,Mouse
Applications:WB,IF/ICC,IHC-p
Modification:Unmodfied/ Total
Source:Monoclonal Mouse
Storage and Stability:-20°C/1 year

$200
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PCNA Monoclonal Antibody(12D10)

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Product Details
Product Name
PCNA Monoclonal Antibody(12D10)
Description
proliferating cell nuclear antigen(PCNA)Homo sapiens. The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq, Jul 2008],
Catalog No
N1295
Reactivity
Human,Rat,Mouse
Applications
WB,IF/ICC,IHC-p
Modification
Unmodfied/ Total
Source
Monoclonal Mouse
Dilution
WB: 1:5000 IHC: 1:200 IF 1:200
Purification
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Concentration
Storage and Stability
-20°C/1 year
Other Name
PCNA; Proliferating cell nuclear antigen; PCNA; Cyclin
Molecular Weight (Da)
28769
Gene Name
PCNA
Protein Name
Proliferating cell nuclear antigen
Human Gene ID
5111
Human Swiss Prot No.
P12004
Immunogen
Synthetic Peptide of PCNA
Specificity
The antibody detects endogenous PCNA protein.
Formulation
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
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Publications (4)
Inhibition of the Ras/ERK1/2 pathway contributes to the protective effect of ginsenoside Re against intimal hyperplasia

Author: Chenying Gao, Kaina Zhang, Fanfan Liang, Wenzhuo Ma, Xixi Jiang, Hongying Wang, Heqin Zhan, Enikö Sonkoly, Hao Hu, Zhenghang Zhao

Date of Publication : 2021-05-20

High mobility group protein B1 (HMGB1) interacts with receptor for advanced glycation end products (RAGE) to promote airway smooth muscle cell proliferation through ERK and NF-κB pathways

Author: Dongming Qu, Zhougui Ling, Xiaoyu Tan, Yan Chen, Qinghua Huang, Mengze Li, Tangjuan Liu, Changchun Hou, Yiqiang Chen

Date of Publication : 2019-09-01

Huaier Restrains Proliferative and Migratory Potential of Hepatocellular Carcinoma Cells Partially Through Decreased Yes-Associated Protein 1

Author: Liang Shan, Yan Li, Hongyuan Jiang, Yuquan Tao, Zijun Qian, Lan Li, Feng Cai, Lifang Ma, Yongchun Yu

Date of Publication : 2017-11-06

CD137–CD137L interaction modulates neointima formation and the phenotype transformation of vascular smooth muscle cells via NFATc1 signaling

Author: Zhong, Wei, Li, Bo, Yang, Ping, Chen, Rui, Wang, Cuiping, Wang, Zhongqun, Shao, Chen, Yuan, Wei, Yan, Jinchuan

Date of Publication : 2017-08-02

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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