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Primary Antibodies
ERCC1 Monoclonal Antibody(1B10)
ERCC1 Monoclonal Antibody(1B10)

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: N1343
Reactivity:Human
Applications:WB,IHC-p,IF(paraffin section),
Modification:Unmodfied/ Total
Source:Monoclonal Mouse
Storage and Stability:-20°C/1 year

$160
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ERCC1 Monoclonal Antibody(1B10)

Western blot analysis of 1) Hela. 2) HepG2. 3) 293T. 4) Jurkat. diluted at 1:2000. cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003.Inventbiotech.MN.USA).

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Product Details
Product Name
ERCC1 Monoclonal Antibody(1B10)
Description
The product of this gene functions in the nucleotide excision repair pathway, and is required for the repair of DNA lesions such as those induced by UV light or formed by electrophilic compounds including cisplatin. The encoded protein forms a heterodimer with the XPF endonuclease (also known as ERCC4), and the heterodimeric endonuclease catalyzes the 5' incision in the process of excising the DNA lesion. The heterodimeric endonuclease is also involved in recombinational DNA repair and in the repair of inter-strand crosslinks. Mutations in this gene result in cerebrooculofacioskeletal syndrome, and polymorphisms that alter expression of this gene may play a role in carcinogenesis. Multiple transcript variants encoding different isoforms have been found for this gene. The last exon of this gene overlaps with the CD3e molecule, epsilon associated protein ge
Catalog No
N1343
Reactivity
Human
Applications
WB,IHC-p,IF(paraffin section),
Modification
Unmodfied/ Total
Source
Monoclonal Mouse
Dilution
IHC-p: 100-300.WB: 1:1000
Purification
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Concentration
Storage and Stability
-20°C/1 year
Other Name
ERCC1; DNA excision repair protein ERCC-1
Molecular Weight (Da)
32562
Gene Name
ERCC1
Protein Name
DNA excision repair protein ERCC-1
Human Gene ID
2067
Human Swiss Prot No.
P07992
Immunogen
Synthetic Peptide of ERCC1
Specificity
The antibody detects endogenous ERCC1 proteins.
Formulation
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
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Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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