cAMP responsive element binding protein 1(CREB1)Homo sapiens. This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in several transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016],
Catalog No
N1516
Reactivity
Human,Mouse
Applications
WB,IHC-p,IF(paraffin section)
Modification
Unmodfied/ Total
Source
Monoclonal Mouse
Dilution
WB: 1:500-1000 IHC: 1:100-200
Purification
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
Concentration
Storage and Stability
-20°C/1 year
Other Name
CREB1; Cyclic AMP-responsive element-binding protein 1; CREB-1; cAMP-responsive element-binding protein 1
Molecular Weight (Da)
Gene Name
CREB1
Protein Name
Cyclic AMP-responsive element-binding protein 1
Human Gene ID
1385
Human Swiss Prot No.
P16220
Immunogen
Recombinant Protein of CREB-1
Specificity
The antibody detects endogenous CREB-1 protein.
Formulation
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
