Fos proto-oncogene, AP-1 transcription factor subunit(FOS) Homo sapiens. The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death. [provided by RefSeq, Jul 2008],
Catalog No
N1525
Reactivity
Human,Rat,Mouse
Applications
WB,IHC-p,IF(paraffin section)
Modification
Unmodfied/ Total
Source
Monoclonal Mouse
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Purification
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
-20°C/1 year
Other Name
Proto-oncogene c-Fos (Cellular oncogene fos) (G0/G1 switch regulatory protein 7)
Molecular Weight (Da)
Gene Name
FOS
Protein Name
Proto-oncogene c-Fos (Cellular oncogene fos) (G0/G1 switch regulatory protein 7)
Human Gene ID
2353
Human Swiss Prot No.
P01100
Immunogen
Recombinant Protein of c-Fos
Specificity
The antibody detects endogenous c-fos protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.