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Primary Antibodies
ERK1/2 mouse Monoclonal Antibody(1H4)
ERK1/2 mouse Monoclonal Antibody(1H4)

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: N1659
Reactivity:Human,Rat,Mouse
Applications:WB,IHC-p,IF(paraffin section)
Modification:Unmodfied/ Total
Source:Monoclonal Mouse
Storage and Stability:-20°C/1 year

$160
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ERK1/2 mouse Monoclonal Antibody(1H4)

Western blot analysis of 1) Hela Cell Lysate. 2)Mouse Brain Tissue Lysate. 3) Rat Brain Tissue Lysate using ERK1/2 Mouse mAb diluted at 1:2000.

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Product Details
Product Name
ERK1/2 mouse Monoclonal Antibody(1H4)
Description
The protein encoded byThis gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described. [provided by RefSeq, Jul 2008],
Catalog No
N1659
Reactivity
Human,Rat,Mouse
Applications
WB,IHC-p,IF(paraffin section)
Modification
Unmodfied/ Total
Source
Monoclonal Mouse
Dilution
WB 1:1000-2000, IHC 1:100-200
Purification
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Concentration
1 mg/ml
Storage and Stability
-20°C/1 year
Other Name
MAPK1/MAPK3
Molecular Weight (Da)
Gene Name
MAPK1/MAPK3
Protein Name
MAPK1/MAPK3
Human Gene ID
5594/5595
Human Swiss Prot No.
P27361/P28482
Immunogen
Synthetic Peptide of ERK1/2 at AA range of 140-220
Specificity
ERK1/2 protein detects endogenous levels of MAPK1/MAPK3
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Publications (10)
Proliferatins suppress lipopolysaccharide-induced inflammation via inhibition of the NF-κB and MAPK signaling pathways. BIOORGANIC CHEMISTRY2022 Jul;124:105810. Mouse RAW264.7 macrophages

Author: Available in link provided

Date of Publication : Available in link provided

Network Pharmacology-Based Strategy to Identify the Pharmacological Mechanisms of Pulsatilla Decoction against Crohn's Disease.. Frontiers in Pharmacology2022 Apr;13:844685-844685. Human,Mouse 1:1000,1:300 colon tissues

Author: Available in link provided

Date of Publication : Available in link provided

ANGPTL1 Interacts with Integrin α1β1 to Suppress HCC Angiogenesis and Metastasis by Inhibiting JAK2/STAT3 Signaling. CANCER RESEARCH 2017 Nov 01 WB Human HUVECs

Author: Available in link provided

Date of Publication : Available in link provided

Effect of cold stress on the MAPK pathway and lipidomics on muscle of Takifugu fasciatus. AQUACULTURE Aquaculture. 2021 Jul;540:736691 WB Fish 1:1500 Muscles

Author: Available in link provided

Date of Publication : Available in link provided

HSP90 inhibitor AUY922 can reverse Fulvestrant induced feedback reaction in human breast cancer cells. CANCER SCIENCE 2017 May 19 WB Human MCF-7 cell，T47D cell

Author: Available in link provided

Date of Publication : Available in link provided

Poly-L-Arginine Induces Apoptosis of NCI-H292 Cells via ERK1/2 Signaling Pathway. Journal of Immunology Research J Immunol Res. 2018;2018:3651743 WB Human 1 : 500 NCI-H292 cell

Author: Available in link provided

Date of Publication : Available in link provided

Cyanidin-3-glucoside Regulates Osteoblast Differentiation via the ERK1/2 Signaling Pathway. ACS Omega Acs Omega. 2021;6(7):4759–4766 WB Mouse MC3T3-E1 cell

Author: Available in link provided

Date of Publication : Available in link provided

Astragalus Polysaccharide Inhibits Ionizing Radiation-Induced Bystander Effects by Regulating MAPK/NF-κB Signaling Pathway in Bone Mesenchymal Stem Cells (BMSCs). MEDICAL SCIENCE MONITOR Med Sci Monitor. 2018; 24: 4649–4658 WB Human BMSCs

Author: Available in link provided

Date of Publication : Available in link provided

C-X-C chemokine receptor type 7 antibody enhances neural plasticity after ischemic stroke Neural Regeneration Research Shan-Shan Zhao WB Rat striatum

Author: Available in link provided

Date of Publication : Available in link provided

Effect of the Pulsatilla decoction n-butanol extract on vulvovaginal candidiasis caused by Candida glabrata and on its virulence factors FITOTERAPIA Jiaping Zhang WB Mouse vaginal tissue

Author: Available in link provided

Date of Publication : Available in link provided

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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