mitogen-activated protein kinase 3(MAPK3)Homo sapiens. The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described. [provided by RefSeq, Jul 2008],
Catalog No
N1659
Reactivity
Human,Rat,Mouse
Applications
WB,IHC-p,IF(paraffin section)
Modification
Unmodfied/ Total
Source
Monoclonal Mouse
Dilution
WB 1:1000-2000, IHC 1:100-200
Purification
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Concentration
1 mg/ml
Storage and Stability
-20°C/1 year
Other Name
MAPK1/MAPK3
Molecular Weight (Da)
Gene Name
MAPK1/MAPK3
Protein Name
MAPK1/MAPK3
Human Gene ID
5594/5595
Human Swiss Prot No.
P27361/P28482
Immunogen
Synthetic Peptide of ERK1/2 at AA range of 140-220
Specificity
ERK1/2 protein detects endogenous levels of MAPK1/MAPK3
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
